Results 31 to 40 of about 398,735 (283)
Mixing signs and bones: John Deely’s case for global semiosis
Sign Systems Studies, 2013 The article develops a critique of John Deely’s ontological realism, specifically in its relevance for the project of global semiotics. Deely, whose theorizations rely heavily on the pre-modern philosophical systems of Thomas Aquinas and the Latin ...
Petre Petrov
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Coordination of Space and Unity of Science [PDF]
, 2000 In this essay, I explore a metaphor in geometry for the debate between the unity and the disunity of science, namely, the possibility of putting a global coordinate system (or a chart) on a manifold. I explain why the former is a good metaphor that shows
Liu, Chuang
core
A Comparative Study of the Transmission from Plurality to Oneness in Plato and MullaSadra's Ontology [PDF]
حکمت معاصر, 2014 Plato on the basis of his unifier viewpoint offered the theory of Idea and other cosmological related to creation and the chain and arrangement of beings. He also placed the principal of Goodness in the climax of the pyramid of his ontology, and by which
Zahra Mohammadi Mohammadieh +1 more
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Beyond Pluralism: Esoteric Unity of Religions and the Ontological Reframing of Comparative Theology [PDF]
Pharos Journal of TheologyThis article examines the epistemological limitations of modern religious pluralism in comparative theology and proposes perennial philosophy as a metaphysical alternative.
M. Nawa Syarif Fajar Sakti +4 more
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Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Unity of Existence from AllamehTabatabaaii’s point of view [PDF]
حکمت اسرا, 2013 The issue of the unity of existence is one of the major ontological issues which has come into being in mystic atmospheres and has gradually entered philosophy as well and influenced it to the point that accepting or rejecting it would overshadow all ...
Seyed Mahmoud Nabavian +1 more
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The motive of brotherhood in A. S. Khomyakov’s works [PDF]
Вестник Свято-Филаретовского институтаThe article is devoted to the problem of actualizing the motive of brotherhood in various spheres of A. S. Khomyakov’s works, identifying the relationships between the ecclesiological theory of the fraternal unity of the church community as “the grace
Nepoklonova E. O.
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The Unity of Epistemology and Ontology as an Essential Interpretation of Scientific Realism
Siberian Journal of Philosophy, 2020 Epistemology and ontology are usually regarded as independent philosophical disciplines. However, the idea of their unity provides the basis for the correct interpretation of the concept of scientific realism as the development of the idea of methodological unity in science, which allows one to distinguish various subject areas, but approach them ...
openaire +2 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source