Results 51 to 60 of about 415,005 (284)

The motive of brotherhood in A. S. Khomyakov’s works [PDF]

Вестник Свято-Филаретовского института
The article is devoted to the problem of actualizing the motive of brotherhood in various spheres of A. S. Khomyakov’s works, identifying the relationships between the ecclesiological theory of the fraternal unity of the church community as “the grace
Nepoklonova E. O.
doaj   +1 more source

The Unity of Epistemology and Ontology as an Essential Interpretation of Scientific Realism

Siberian Journal of Philosophy, 2020
Epistemology and ontology are usually regarded as independent philosophical disciplines. However, the idea of their unity provides the basis for the correct interpretation of the concept of scientific realism as the development of the idea of methodological unity in science, which allows one to distinguish various subject areas, but approach them ...
openaire   +2 more sources

Application for Subvention by Organization of African Trade Union Unity [PDF]

, 1981
Council of Ministers Thirty-Sixth Ordinary Session February 1981 Addis AbabaA report on the application for subvention from the Organization of African Unity by the Organization of African Trade Union Unity highlighting its activities as well as its ...
Organization of African Unity
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The Influence of Ibn Arabi's Ontological Foundations on Formation of the Embodiment of Acts [PDF]

حکمت صدرایی, 2020
"The embodiment of deeds", or the ontological relationship of human actions and beliefs with pleasures and pains of afterlife, is one of the most important and complex issues raised in resurrection.
مهدی صفایی اصل, صدرالدین طاهری موسوی   +1 more
doaj  

GREGORY PALAMAS ’ ONTOLOGY AS THEORETICAL FOUNDATION OF AXIOLOGICAL ASPECTS OF THE PHILOSOPHY OF „ALL-UNITY“ [PDF]

Konštantínove listy/Constantine's Letters, 2016
The influence of hesychastic traditions on the Russian culture can be found in cultural practices since the 15th century. In the 19th century, the tradition of hesychasm determined semantic coordinates of ontological aspects of the philosophy of "All-Unity". This strategy is aimed at creation of unity which would have ontological basis.
Kletskova, I., Lyahchylin, A.
openaire   +3 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

From Platonic anamnesis to the architectonics of philosophical knowledge: The historical-philosophical status of reminiscence [PDF]

Известия Саратовского университета. Новая серия: Серия Философия. Психология. Педагогика
Introduction. The article explores the phenomenon of reminiscence as a possible method of constructing the history of philosophy, which transforms the Platonic concept of recollection (anamnesis) into a tool for synthesizing universal ideas and ...
Romaschenko, Maria A., Romashchenko, Alexander Alexandrovich   +1 more
doaj   +1 more source