Results 31 to 40 of about 113,360 (251)

Computationally Efficient Context-Free Named Entity Disambiguation with Wikipedia

Information, 2022
The induction of the semantics of unstructured text corpora is a crucial task for modern natural language processing and artificial intelligence applications.
Michael Angelos Simos, Christos Makris
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Legal Ontologies for the spanish e-Government [PDF]

, 2006
The Electronic Government is a new field of applications for the semantic web where ontologies are becoming an important research technology. The e-Government faces considerable challenges to achieve interoperability given the semantic differences of ...
Villazón-Terrazas, B., Fernando Ortiz-Rodríguez, Asunción Gómez-Pérez, Boris Villazón-Terrazas, Gómez-Pérez, A., Ortiz Rodríguez, F.   +5 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Empirical analysis of impacts of instance-driven changes in ontologies [PDF]

, 2010
Changes in the characterization of instances in digital contents are one of the rationales to change or evolve ontologies which support the domain. These changes can impacts on one or more of interrelated ontologies.
Abgaz, Yalemisew, Abgaz, Yalemisew Mintsnote, Pahl, Claus, Yalemisew M. Abgaz, Claus Pahl, Muhammad Javed   +5 more
core   +2 more sources

Developing domain ontologies for courseware content [PDF]

, 2005
Ontologies have the potential to play an important role in educational technology. They can be used to represent knowledge about educational content, supporting instructors in creating content or learners in accessing content in a knowledge-guided way ...
Boyce, Sinead, Pahl, Claus
core   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Developing domain ontologies for course content [PDF]

, 2007
Ontologies have the potential to play an important role in instructional design and the development of course content. They can be used to represent knowledge about content, supporting instructors in creating content or learners in accessing content in a
Boyce, Sinead, Pahl, Claus
core   +2 more sources

Knowledge Graphs’ Ontologies and Applications for Energy Efficiency in Buildings: A Review

Energies, 2022
The Architecture, Engineering and Construction (AEC) industry has been utilizing Decision Support Systems (DSSs) for a long time to support energy efficiency improvements in the different phases of a building’s life cycle. In this context, there has been
Filippos Lygerakis, Nikos Kampelis, Dionysia Kolokotsa   +2 more
doaj   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source