Results 41 to 50 of about 147,101 (317)

Engineering ontologies [PDF]

open access: yesInternational Journal of Human-Computer Studies, 1997
We analyse the construction as well as the role of ontologies in knowledge sharing and reuse for complex industrial applications. In this article, the practical use of ontologies in large-scale applications not restricted to knowledge-based systems is demonstrated, for the domain of engineering systems modelling, simulation and design.
Borst, P., Akkermans, H., Top, J.L.
openaire   +3 more sources

Matching disease and phenotype ontologies in the ontology alignment evaluation initiative

open access: yesJournal of Biomedical Semantics, 2017
Background The disease and phenotype track was designed to evaluate the relative performance of ontology matching systems that generate mappings between source ontologies.
Ian Harrow   +9 more
doaj   +1 more source

Enhancing Learning Personalization in Educational Environments through Ontology-Based Knowledge Representation

open access: yesComputers, 2023
In the digital age, the personalization of learning has become a critical priority in education. This article delves into the cutting-edge of educational innovation by exploring the essential role of ontology-based knowledge representation in ...
William Villegas-Ch   +1 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

From Ontology to Ontologies to Trans-Ontology

open access: yesForum Philosophicum, 2016
This paper describes the implications of the transition from Ontology conceived as fundamental metaphysical logos to ontologies construed as postmodern historical applications of this, and then, finally, to Trans-Ontology as the ultimate, futuristic innovation of Transhumanism.
openaire   +1 more source

Semantically-Aware Retrieval of Oceanographic Phenomena Annotated on Satellite Images

open access: yesInformation, 2021
Scientists in the marine domain process satellite images in order to extract information that can be used for monitoring, understanding, and forecasting of marine phenomena, such as turbidity, algal blooms and oil spills.
Vasilis Kopsachilis   +6 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Ontology for immunogenetics: the IMGT-ONTOLOGY [PDF]

open access: yesBioinformatics, 1999
Abstract Motivation: IMGT, the international ImMunoGene- Tics database (http://imgt.cines.fr:8104), created by M.-P. Lefranc, is an integrated database specializing in antigen receptors (immunoglobulins and T-cell receptors) and major histocompatibility complex (MHC) of all vertebrate species.
Giudicelli, Véronique   +1 more
openaire   +3 more sources

Semantic Ontologies for Complex Healthcare Structures: A Scoping Review

open access: yesIEEE Access, 2023
The healthcare environment is made up of highly complicated interactions between many technologies, activities, and people. Ensuring a solid communication between them is vital to ease the healthcare management.
Alessio Luschi   +4 more
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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