Results 51 to 60 of about 300,638 (342)
How orthogonal are the OBO Foundry ontologies?
Journal of Biomedical Semantics, 2011 Background Ontologies in biomedicine facilitate information integration, data exchange, search and query of biomedical data, and other critical knowledge-intensive tasks.
Ghazvinian Amir +2 more
doaj +1 more source
Semantic Network Analysis of Ontologies [PDF]
, 2011 A key argument for modeling knowledge in ontologies is the easy re-use and re-engineering of the knowledge. However, current ontology engineering tools provide only basic functionalities for analyzing ontologies.
Hoser, Bettina +4 more
core
International Journal of Human-Computer Studies, 1997 We analyse the construction as well as the role of ontologies in knowledge sharing and reuse for complex industrial applications. In this article, the practical use of ontologies in large-scale applications not restricted to knowledge-based systems is demonstrated, for the domain of engineering systems modelling, simulation and design.
Borst, P., Akkermans, H., Top, J.L.
openaire +3 more sources
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Matching disease and phenotype ontologies in the ontology alignment evaluation initiative
Journal of Biomedical Semantics, 2017 Background The disease and phenotype track was designed to evaluate the relative performance of ontology matching systems that generate mappings between source ontologies.
Ian Harrow +9 more
doaj +1 more source
Computers, 2023 In the digital age, the personalization of learning has become a critical priority in education. This article delves into the cutting-edge of educational innovation by exploring the essential role of ontology-based knowledge representation in ...
William Villegas-Ch +1 more
doaj +1 more source
Desiderata for an ontology of diseases for the annotation of biological datasets. [PDF]
, 2009 There is a plethora of disease ontologies available, all potentially useful for the annotation of biological datasets. We define seven desirable features for such ontologies and examine whether or not these features are supported by eleven disease ...
Anita Burgun, Olivier Bodenreider
core +1 more source
From Ontology to Ontologies to Trans-Ontology
Forum Philosophicum, 2016 This paper describes the implications of the transition from Ontology conceived as fundamental metaphysical logos to ontologies construed as postmodern historical applications of this, and then, finally, to Trans-Ontology as the ultimate, futuristic innovation of Transhumanism.
openaire +1 more source
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Semantically-Aware Retrieval of Oceanographic Phenomena Annotated on Satellite Images
Information, 2021 Scientists in the marine domain process satellite images in order to extract information that can be used for monitoring, understanding, and forecasting of marine phenomena, such as turbidity, algal blooms and oil spills.
Vasilis Kopsachilis +6 more
doaj +1 more source