Results 51 to 60 of about 581,965 (380)

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

Ontology-Based Personalized Job Recommendation Framework for Migrants and Refugees

Big Data and Cognitive Computing, 2022
Participation in the labor market is seen as the most important factor favoring long-term integration of migrants and refugees into society. This paper describes the job recommendation framework of the Integration of Migrants MatchER SErvice (IMMERSE ...
Dimos Ntioudis, Panagiota Masa, Anastasios Karakostas, Georgios Meditskos, Stefanos Vrochidis, Ioannis Kompatsiaris   +5 more
doaj   +1 more source

Ontologies for Bioinformatics

Bioinformatics and Biology Insights, 2008
The past twenty years have witnessed an explosion of biological data in diverse database formats governed by heterogeneous infrastructures. Not only are semantics (attribute terms) different in meaning across databases, but their organization varies widely.
Nadine Schuurman, Agnieszka Leszczynski
openaire   +6 more sources

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Searching and ranking ontologies on the Semantic Web [PDF]

, 2005
The number of ontologies available online is increasing constantly. Tools that are capable of searching, retrieving, and ranking ontologies are becoming crucial to facilitate ontology search and reuse. In this document, we describe OntoSearch, which is a
Christopher Brewster, Derek Sleeman, Edward Thomas, Harith Alani, How To Cite   +4 more
core   +1 more source

Contextualizing ontologies [PDF]

Journal of Web Semantics, 2004
Ontologies are shared models of a domain that encode a view which is common to a set of different parties. Contexts are local models that encode a party's subjective view of a domain. In this paper, we show how ontologies can be contextualized, thus acquiring certain useful properties that a pure shared approach cannot provide.
Bouquet, Paolo, Giunchiglia, Fausto, F. Van Harmelen, Serafini, Luciano, H. Stuckenschmidt   +4 more
openaire   +4 more sources

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Desiderata for an ontology of diseases for the annotation of biological datasets. [PDF]

, 2009
There is a plethora of disease ontologies available, all potentially useful for the annotation of biological datasets. We define seven desirable features for such ontologies and examine whether or not these features are supported by eleven disease ...
Anita Burgun, Olivier Bodenreider
core   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

Conjunctive query inseparability of OWL 2 QL TBoxes [PDF]

, 2011
The OWL2 profile OWL 2 QL, based on the DL-Lite family of description logics, is emerging as a major language for developing new ontologies and approximating the existing ones. Its main application is ontology based data access, where ontologies are used
Konev, B., Kontchakov, Roman, Michel, L., Schneider, T., Wolter, F., Zakharyaschev, Michael   +5 more
core   +1 more source