Results 61 to 70 of about 300,638 (342)

Using Cross-Lingual Explicit Semantic Analysis for Improving Ontology Translation [PDF]

open access: yes, 2012
Semantic Web aims to allow machines to make inferences using the explicit conceptualisations contained in ontologies. By pointing to ontologies, Semantic Web-based applications are able to inter-operate and share common information easily.
Aggarwal, Nitish   +3 more
core   +2 more sources

Ontology for immunogenetics: the IMGT-ONTOLOGY [PDF]

open access: yesBioinformatics, 1999
Abstract Motivation: IMGT, the international ImMunoGene- Tics database (http://imgt.cines.fr:8104), created by M.-P. Lefranc, is an integrated database specializing in antigen receptors (immunoglobulins and T-cell receptors) and major histocompatibility complex (MHC) of all vertebrate species.
Giudicelli, Véronique   +1 more
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Semantic Ontologies for Complex Healthcare Structures: A Scoping Review

open access: yesIEEE Access, 2023
The healthcare environment is made up of highly complicated interactions between many technologies, activities, and people. Ensuring a solid communication between them is vital to ease the healthcare management.
Alessio Luschi   +4 more
doaj   +1 more source

Conceptual modelling and the quality of ontologies: A comparison between object-role modelling and the object paradigm [PDF]

open access: yes, 2010
Ontologies are key enablers for sharing precise and machine-understandable semantics among different applications and parties. Yet, for ontologies to meet these expectations, their quality must be of a good standard.
Al-Asswad, MM   +3 more
core  

Ontological Overhearing [PDF]

open access: yes, 2002
The collaboration between two intelligent agents can be greatly enhanced if a third agent, who has some understanding of the communication between the first two, intervenes giving appropriate information or acting helpfully without having been explicitly involved.
Aiello, M.   +3 more
openaire   +4 more sources

Managing Multiple Ontologies and Ontology Evolution in Ontologging [PDF]

open access: yes, 2002
Ontologging is an ontology-driven environment to enable next generation knowledge management applications building on Semantic Web technology. In this paper we first present the conceptual architecture underlying Ontologging. Second, we focus on two important challenges for ontology-based knowledge management, namely the supporting multiple ontologies ...
Maedche, Alexander   +4 more
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Metrics and methods for comparative ontology evaluation

open access: yesCiência da Informação, 2017
While progress has been made toward describing the need for ontology evaluation and offering proposals concerning what properties to measure and how, work remains to develop ontology evaluation as a rigorous discipline.
Amanda Hicks
doaj  

Metrics for ranking ontologies [PDF]

open access: yes, 2006
Representing knowledge using domain ontologies has shown to be a useful mechanism and format for managing and exchanging information. Due to the difficulty and cost of building ontologies, a number of ontology libraries and search engines are coming to ...
Alani, Harith, Brewster, Christopher
core   +3 more sources

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