Results 61 to 70 of about 514,391 (335)
BioPortal: ontologies and integrated data resources at the click of a mouse
Nucleic Acids Res., 2009 Biomedical ontologies provide essential domain knowledge to drive data integration, information retrieval, data annotation, natural-language processing and decision support. BioPortal (http://bioportal.bioontology.org) is an open repository of biomedical
P. Whetzel +9 more
semanticscholar +1 more source
International Journal of Human-Computer Studies, 1997 We analyse the construction as well as the role of ontologies in knowledge sharing and reuse for complex industrial applications. In this article, the practical use of ontologies in large-scale applications not restricted to knowledge-based systems is demonstrated, for the domain of engineering systems modelling, simulation and design.
Borst, P., Akkermans, H., Top, J.L.
openaire +3 more sources
Desiderata for an ontology of diseases for the annotation of biological datasets. [PDF]
, 2009 There is a plethora of disease ontologies available, all potentially useful for the annotation of biological datasets. We define seven desirable features for such ontologies and examine whether or not these features are supported by eleven disease ...
Anita Burgun, Olivier Bodenreider
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Matching disease and phenotype ontologies in the ontology alignment evaluation initiative
Journal of Biomedical Semantics, 2017 Background The disease and phenotype track was designed to evaluate the relative performance of ontology matching systems that generate mappings between source ontologies.
Ian Harrow +9 more
doaj +1 more source
Computers, 2023 In the digital age, the personalization of learning has become a critical priority in education. This article delves into the cutting-edge of educational innovation by exploring the essential role of ontology-based knowledge representation in ...
William Villegas-Ch +1 more
doaj +1 more source
From Ontology to Ontologies to Trans-Ontology
Forum Philosophicum, 2016 This paper describes the implications of the transition from Ontology conceived as fundamental metaphysical logos to ontologies construed as postmodern historical applications of this, and then, finally, to Trans-Ontology as the ultimate, futuristic innovation of Transhumanism.
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Semantic Network Analysis of Ontologies [PDF]
, 2011 A key argument for modeling knowledge in ontologies is the easy re-use and re-engineering of the knowledge. However, current ontology engineering tools provide only basic functionalities for analyzing ontologies.
Hoser, Bettina +4 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Semantically-Aware Retrieval of Oceanographic Phenomena Annotated on Satellite Images
Information, 2021 Scientists in the marine domain process satellite images in order to extract information that can be used for monitoring, understanding, and forecasting of marine phenomena, such as turbidity, algal blooms and oil spills.
Vasilis Kopsachilis +6 more
doaj +1 more source