Results 61 to 70 of about 581,965 (380)

How orthogonal are the OBO Foundry ontologies?

open access: yesJournal of Biomedical Semantics, 2011
Background Ontologies in biomedicine facilitate information integration, data exchange, search and query of biomedical data, and other critical knowledge-intensive tasks.
Ghazvinian Amir   +2 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Ontology (Science) [PDF]

open access: yes, 2008
Increasingly, in data-intensive areas of the life sciences, experimental results are being described in algorithmically useful ways with the help of ontologies.
Barry Smith
core   +2 more sources

EPPO ontology: a semantic-driven approach for plant and pest codes representation

open access: yesFrontiers in Artificial Intelligence, 2023
The agricultural industry and regulatory organizations define strategies and build tools and products for plant protection against pests. To identify different plants and their related pests and avoid inconsistencies between such organizations, an agreed
Aarón Ayllón-Benitez   +9 more
doaj   +1 more source

The role of ontologies in biological and biomedical research: a functional perspective

open access: yesBriefings Bioinform., 2015
Ontologies are widely used in biological and biomedical research. Their success lies in their combination of four main features present in almost all ontologies: provision of standard identifiers for classes and relations that represent the phenomena ...
R. Hoehndorf, P. Schofield, G. Gkoutos
semanticscholar   +1 more source

An ontological analysis of some biological ontologies [PDF]

open access: yesFrontiers in Genetics, 2012
The functional importance of biological entities makes their understanding, analysis, and representation essential in modern biology. Arguably, semantic representation necessary for machine interoperability is a far more difficult task than syntactic representation, necessitating conceptual schema and ontologies for in-silico biological knowledge ...
openaire   +4 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

A platform for semantic web studies [PDF]

open access: yes, 2010
The Semantic Web can be seen as a large, heterogeneous network of ontologies and semantic documents. Characterizing these ontologies, the way they relate and the way they are organized can help in better understanding how knowledge is produced and ...
Allocca, Carlo   +2 more
core  

Matching disease and phenotype ontologies in the ontology alignment evaluation initiative

open access: yesJournal of Biomedical Semantics, 2017
Background The disease and phenotype track was designed to evaluate the relative performance of ontology matching systems that generate mappings between source ontologies.
Ian Harrow   +9 more
doaj   +1 more source

Institutional Ontology as an Ontology of Types

open access: yesPhenomenology and Mind, 2012
Phenomenology and Mind, No 3 (2012): Norms, Values, Society: Phenomenological and Ontological ...
openaire   +3 more sources

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