Results 91 to 100 of about 1,266,792 (389)

Data-Driven Dialogue Models: Applying Formal and Computational Tools to the Study of Financial And Moral Dialogues

open access: yesStudies in Logic, Grammar and Rhetoric, 2020
This paper proposes two formal models for understanding real-life dialogues, aimed at capturing argumentative structures performatively enacted during conversations.
Yaskorska-Shah Olena
doaj   +1 more source

OntoEng: A design method for ontology engineering in information systems [PDF]

open access: yes, 2009
This paper addresses the design problem relating to ontology engineering in the discipline of information systems. Ontology engineering is a realm that covers issues related to ontology development and use throughout its life span.
Al-Debei, MM, Fitzgerald, G
core  

Working with Ontologies

open access: yes, 2016
Ontologies are powerful and popular tools to encode data in a structured format and manage knowledge. A large variety of existing ontologies offer users access to biomedical knowledge. This chapter contains a short theoretical background of ontologies and introduces two notable examples: The Gene Ontology and the ontology for Biological Pathways ...
Kramer, Frank, Beißbarth, Tim
openaire   +4 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Ontology: Towards a new synthesis [PDF]

open access: yes, 1998
This introduction to the second international conference on Formal Ontology and Information Systems presents a brief history of ontology as a discipline spanning the boundaries of philosophy and information science.
Smith, Barry, Welty, Chris
core  

Natural Language and its Ontology [PDF]

open access: yes, 2019
This paper gives a characterization of the ontology implicit in natural language and the entities it involves, situates natural language ontology within metaphysics, and responds to Chomskys' dismissal of externalist ...
Moltmann, Friederike
core   +1 more source

ROBOT: A Tool for Automating Ontology Workflows

open access: yesBMC Bioinformatics, 2019
Ontologies are invaluable in the life sciences, but building and maintaining ontologies often requires a challenging number of distinct tasks such as running automated reasoners and quality control checks, extracting dependencies and application-specific
Rebecca C. Jackson   +5 more
semanticscholar   +1 more source

Ontologies and Ontological Representation

open access: yesOvidius University Annals: Economic Sciences Series, 2020
The present paper aims to present the main theoretical and practical aspects of what ontology and knowledge bases mean, having the role of providing as precise information as possible. Ontologies are considered to be a vocabulary of concepts, and the purpose of this "vocabulary" is to ensure a semantically based level of knowledge based on semantics in
Tudor Colomeischi, Eugenia Iancu
openaire   +1 more source

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