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Working Document on Gloss Ontology [PDF]

open access: yes, 2010
This document describes the Gloss Ontology. The ontology and associated class model are organised into several packages.
Coutaz, Joelle   +7 more
core   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Change Management: The Core Task of Ontology Versioning and Evolution

open access: yes, 2005
Change management as a key issue in ontology versioning and evolution is still not fully addressed, which to some extent forms a barrier against the smooth process of ontology evolution.
Alani, Harith   +2 more
core  

A community based approach for managing ontology alignments [PDF]

open access: yes, 2008
The Semantic Web is rapidly becoming a defacto distributed repository for semantically represented data, thus leveraging on the added on value of the network effect.
Alani, Harith   +2 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Demo: A community based approach for managing ontology alignments [PDF]

open access: yes, 2008
The Semantic Web is rapidly becoming a defacto distributed repository for semantically represented data, thus leveraging on the added on value of the network effect.
Alani, Harith   +3 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Building a family ontology to meet consistency criteria [PDF]

open access: yes, 2015
Semantic web is an extension of the current web in which the existing information on the web are organized and encoded more meaningfully using ontology language, thus enabling effective communication among machines and humans. Ontology is the backbone
Tan, Mee Ting
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Risk as a wicked problem in planning: the role of future non-knowledge

open access: yesTeMA: Journal of Land Use, Mobility and Environment
Dealing with spatial organization, planning and design has to cope with something that is not (not yet or never will be) there. This is a matter of knowledge and of knowledge management, a matter for times to come: so in knowledge management the facet of
Maria Rosaria Stufano Melone   +1 more
doaj   +1 more source

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