Results 111 to 120 of about 491,544 (310)

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

Completion of Ontologies and Ontology Networks.

open access: yes, 2017
The World Wide Web contains large amounts of data, and in most cases this data has no explicit structure. The lack of structure makes it difficult for automated agents to understand and use such data. A step towards a more structured World Wide Web is the Semantic Web, which aims at introducing semantics to data on the World Wide Web.
openaire   +2 more sources

Spatiotemporal Drug Delivery via a Neonatal Spinal Cord ECM Hydrogel for Biomimetic Microenvironment Remodeling After Spinal Cord Injury

open access: yesAdvanced Functional Materials, EarlyView.
A biomimetic hydrogel derived from neonatal spinal cord ECM (DNSCM) delivers LAMB2 protein and ISP peptide to remodel the inhibitory injury microenvironment. The system sustains drug release, upregulates pro‐regenerative LAMB2, downregulates inhibitory CSPG, and promotes axonal regeneration.
Shiyu Fu   +8 more
wiley   +1 more source

Some Issues on Ontology Integration

open access: yes, 1999
The word integration has been used with different meanings in the ontology field. This article aims at clarifying the meaning of the word “integration” and presenting some of the relevant work done in integration.
Pinto, H.S.   +5 more
core  

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

open access: yesAdvanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim   +9 more
wiley   +1 more source

Masculinity and Man’s Problems in Presentations of Contemporary Young People [PDF]

open access: yesJournal of Interdisciplinary Sciences, 2019
This study is conducted from the standpoint of the modern interdisciplinary direction in social sciences - boyhood studies – that initiates the necessity of studying the ideas of modern youth about masculinity and specific male and youth problems in ...
Ekaterina Khitruk
doaj  

Infusible Extracellular Matrix Biomaterial Enhances Cell‐Specific Pro‐Repair Responses Following Acute Myocardial Infarction

open access: yesAdvanced Healthcare Materials, EarlyView.
We measure the cell‐specific responses of administering infusible ECM (iECM) in acute myocardial infarction (MI) across multiple timepoints. Using single‐nucleus RNA sequencing and spatial transcriptomics, we measure macrophage activation, fibroblast remodeling, increased vascular development, lymphangiogenesis, cardioprotection, and neurogenesis ...
Joshua M. Mesfin   +18 more
wiley   +1 more source

Ontology Change Management in Protégé

open access: yes, 2005
Ontology schemas tend to change and evolve over time to meet new requirements. This change may invalidate dependent applications if there is no dynamic adaptation to the changes made to underlying ontologies.
Liang, Yaozhong   +2 more
core  

Chamber‐Specific Decellularized Extracellular Matrices Differentially Modulate Cardiomyocyte Subtypes to Drive Engineered Heart Tissue Development and Function

open access: yesAdvanced Healthcare Materials, EarlyView.
Chamber‐specific decellularized extracellular matrices (ECMs) were developed, preserving native proteomic profiles of ventricular and atrial myocardium. These innate biochemical cues differentially modulate cardiomyocyte subtypes to drive engineered heart tissue development and function, highlighting the importance of incorporating regional ECM cues in
Dong Gyu Hwang   +7 more
wiley   +1 more source

Working with Ontologies

open access: yes, 2016
Ontologies are powerful and popular tools to encode data in a structured format and manage knowledge. A large variety of existing ontologies offer users access to biomedical knowledge. This chapter contains a short theoretical background of ontologies and introduces two notable examples: The Gene Ontology and the ontology for Biological Pathways ...
Kramer, Frank, Beißbarth, Tim
openaire   +4 more sources

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