Results 121 to 130 of about 491,544 (310)
This study presents a bioengineered assembloid (ASM) system combining glioblastoma (GBM) cells in oxidized alginate (OA) microgels with dorsal organoids (DOs). This model simulates brain tumor‐host interactions, revealing enhanced GBM invasion, altered gene expression, and aggressive infiltration patterns, demonstrating ASM as a valuable platform for ...
Chao Liang +17 more
wiley +1 more source
The literary theme ontology for media annotation and information retrieval
Literary theme identification and interpretation is a focal point of literary studies scholarship. Classical forms of literary scholarship, such as close reading, have flourished with scarcely any need for commonly defined literary themes.
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Introduction to the Issue: Contemporary Philosophy of Informatics
Stacewicz Paweł, Koszowy Marcin
doaj +1 more source
A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta +3 more
wiley +1 more source
A layered framework for pattern-based ontology evolution [PDF]
The challenge of ontology-driven modelling of information components is well known in both academia and industry. In this paper, we present a novel approach to deal with customisation and abstraction of ontology-based model evolution.
Abgaz, Yalemisew +6 more
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Microfluidic coaxial extrusion generates size‐controlled 3D lymphatic tubes from primary human dermal lymphatic endothelial cells in a defined four‐component matrix. These engineered vessels self‐organize into stable lymphatic endothelium, maintain selective macromolecular permeability for 30 days, and enable direct comparison with blood endothelial ...
Elsa Mazari‐Arrighi +8 more
wiley +1 more source
Ontologies and their Applications.
Ontologies and their ...
Freitas, Fred +3 more
openaire +4 more sources
We develop a covalent organic framework‐loaded Traditional Chinese Medicine monomer nanodrug delivery system (ISL@bCOF) via boron‐oxygen bonds, a smart response to glucose for delivering AI‐driven isoliquiritigenin (ISL) targeting ZBP1. This dynamic release mechanism, combined with transdermal delivery technology via potent microneedles, can modulate ...
Menghan Zhou +9 more
wiley +1 more source
Graph-based discovery of ontology change patterns [PDF]
Ontologies can support a variety of purposes, ranging from capturing conceptual knowledge to the organisation of digital content and information. However, information systems are always subject to change and ontology change management can pose challenges.
Abgaz, Yalemisew +3 more
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