Results 111 to 120 of about 885,759 (298)
An ontological analysis of some biological ontologies [PDF]
Frontiers in Genetics, 2012 The functional importance of biological entities makes their understanding, analysis, and representation essential in modern biology. Arguably, semantic representation necessary for machine interoperability is a far more difficult task than syntactic representation, necessitating conceptual schema and ontologies for in-silico biological knowledge ...
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NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
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BMC Veterinary Research, 2017 Background Today’s globalised and interconnected world is characterized by intertwined and quickly evolving relationships between animals, humans and their environment and by an escalating number of accessible data for public health.
Laura Contalbrigo +3 more
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Ontology learning for semantic web services [PDF]
, 2009 Semantic Web Services promise automatic service discovery and composition, relying heavily on domain ontology as a core component. With large Web Service repository, manual ontology development is proving a bottleneck (with associated expense and likely ...
Auhood, A, Bell, D, Lycett, M
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Ontology construction from online ontologies [PDF]
, 2006 One of the main hurdles towards a wide endorsement of ontologies is the high cost of constructing them. Reuse of existing ontologies offers a much cheaper alternative than building new ones from scratch, yet tools to support such reuse are still in their infancy.
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Copy Number Variants and Their Association With Intracerebral Hemorrhage Risk: A Case–Control Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Intracerebral Hemorrhage (ICH) is a leading cause of morbidity and mortality worldwide and lacks effective therapeutic interventions. Despite previous studies, the genetic underpinnings of ICH remain poorly understood. We sought to investigate the role of copy number variants (CNVs) in ICH pathophysiology to identify novel ...
Savvina Prapiadou +12 more
wiley +1 more source
Can Ontology Inform Ontologies? [PDF]
, 2009 Traditionally, since it was coined in the early 17th century by German school philosophy, the word "ontology" has been used to name a field of metaphysics as well as distinct metaphysical doctrines. Since the 1990s, the word "ontology" appears increasingly in information sciences, and likewise in fields that have been subjected to `informatisation ...
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Canadian Journal of Philosophy, 2018 Parfit denies that the introduction of reasons into our ontology is costly for his theory. He puts forth two positions to help establish the claim: the Plural Senses View and the Argument from Empty Ontology. I argue that, first, the Plural Senses View for ‘exists’ can be expanded to allow for senses which undermine his ontological claims; second, the ...
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
The Concept of Gender Crossing in the Deirdre McCloskey’s Theory [PDF]
Journal of Interdisciplinary Sciences, 2018 This article explores the concept of gender identity of the famous American economist Deirdre McCloskey. The concept has three key elements: Firstly, gender identity does not directly refer to sexual orientation.
Khitruk Ekaterina
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