Results 131 to 140 of about 1,055,752 (313)

A Survey on Ontologies’ Adaptability and Interoperability

Cybernetics and Information Technologies
Interoperability issues emerge due to differences in the sizes and expressive powers of ontologies. Although ontologies are expressive, they tend to lack flexibility. Research shows that specialized ontologies are not merely advantageous for a particular
Dahir Sarah, Qadi Abderrahim El
doaj   +1 more source

CroMatcher 2.0: A Comprehensive Analysis of the Improved Ontology Matching System

IEEE Access
One of the main challenges in ontology matching is to match ontologies with high accuracy. Therefore, ontology matching systems typically use multiple basic matchers, each targeting a specific ontology component for the matching process.
Marko Gulic, Boris Vrdoljak, Marina Pticek   +2 more
doaj   +1 more source

Deciphering the Role of Cancer Stem Cells in Breast Cancer Brain Colonization Using a Novel Patient‐Derived Model

Advanced Healthcare Materials, EarlyView.
This study shows that stem‐like cells isolated from breast cancer brain metastases drive the spread and growth of tumors in the brain. Among them, a highly adhesive subgroup initiates metastasis and resists many drugs. By closely reflecting patient tumors, these models help identify new targets and improve the development of effective treatments ...
Stefania Faletti, Cristina Richichi, Daniela Osti, Elena Ceccacci, Giovanni Bertalot, Camilla Cerutti, Giuseppina Giardina, Adriana Marinaro, Brunella Costanza, Valentina Gambino, Elena Zaccheroni, Daniela Tosoni, Maria G. Filippone, Marcello Del Corvo, Yinxiu Zhan, Teresa Gravina, Davide Corà, Monica Patanè, Bianca Pollo, Maria Giovanna Jodice, Salvatore Pece, Babette B. Weksler, Ignacio A. Romero, Pierre‐Olivier Couraud, Elisabetta Munzone, Massimiliano Del Bene, Francesco DiMeco, Giuliana Pelicci   +27 more
wiley   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Progressive Ontology Alignment for Meaning Coordination: an Information-Theoretic Foundation

, 2005
We elaborate on the mathematical foundations of the meaning coordination problem that agents face in open environments. We investigate to which extend the Barwise-Seligman theory of information flow provides a faithful theoretical description of the ...
Kalfoglou, Yannis, Schorlemmer, Marco
core  

Some Issues on Ontology Integration [PDF]

, 1999
The word integration has been used with different meanings in the ontology field. This article aims at clarifying the meaning of the word “integration” and presenting some of the relevant work done in integration.
Gómez-Pérez, A., Martins, J.P., Pinto, H.S.   +2 more
core   +3 more sources

Arabic Language Alignment with English Ontologies: Some Ontological Reflections

2018 IEEE 5th International Congress on Information Science and Technology (CiSt), 2018
There have been several attempts to build lexico-conceptual resources by extension of the English WordNet, i.e. by means of translation of English synsets. However, the extension approach is arguable because it assumes that the target resource is isomorphic to English WordNet. Yet, some languages, such as English and Arabic, can be very different.
openaire   +3 more sources

Bottom‐Up Programming of Cell States in Cancer Organoids with Defined Synthetic Adhesion Cues

Advanced Materials, EarlyView.
A bottom‐up biomaterial platform is developed to program transcriptomic states in pancreatic cancer organoids by tuning adhesion cues within synthetic matrices. By combining a Design of Experiments framework with multiobjective optimization, matrix compositions are identified that enrich specific cellular programs like EMT.
Ali Nadernezhad, Verena J. Kast, Dagmar Pette, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner   +6 more
wiley   +1 more source

A Nano‐Interception Strategy for Chronic Heart Failure: Prussian Blue Nanoparticles Disrupt Fibroblast‐Immune Communication via CCL2 Sequestration

Advanced Materials, EarlyView.
A nano‐interception strategy disrupts pathogenic fibroblast–macrophage crosstalk in chronic heart failure. Scalable Prussian blue nanoparticles selectively sequester CCL2 via ultrahigh‐affinity binding, preventing CCR2+ macrophage recruitment and breaking a key fibro‐inflammatory circuit. This approach demonstrates robust efficacy in murine and porcine
Bo Chen, Gao Wei, Guowei Zeng, Haoyu Li, Rongrong Wu, Hongyu Yan, Zijie Zhou, Kai Luo, Xiaoyang Zhang, Cong Li, Longming Huang, Lingyan Cheng, Xinjie Zhang, Jinghao Zheng, Bozhong Shi, Xiaojun Cai, Xiaomin He   +16 more
wiley   +1 more source

An ontology of mechanisms of action in behaviour change interventions [version 2; peer review: 2 approved]

Wellcome Open Research
Background Behaviour change interventions influence behaviour through causal processes called “mechanisms of action” (MoAs). Reports of such interventions and their evaluations often use inconsistent or ambiguous terminology, creating problems for ...
Candice Moore, Alison J. Wright, Verena Schneider, Robert West, Emily Hayes, Janna Hastings, Ella Howes, Susan Michie, Fabiana Lorencatto, Paulina M. Schenk   +9 more
doaj   +1 more source