Results 141 to 150 of about 80,509 (303)

Results of the Ontology Alignment Evaluation Initiative 2021

, 2021
The Ontology Alignment Evaluation Initiative (OAEI) aims at comparing ontology matching systems on precisely defined test cases. These test cases can be based on ontologies of different levels of complexity and use different evaluation modalities (e.g ...
Vatascinová, Jana,, Fundulaki, Irini,, Laadhar, Amir,, Li, Ying,, Paulheim, Heiko,, Zhou, Lu,, Harrow, Ian,, Hertling, Sven,, Roussey, Catherine,, Amardeilh, Florence,, Shvaiko, Pavel,, Yaman, Beyza,, Fallatah, Omaima,, Ibanescu, Liliana,, Lambrix, Patrick,, Amini, Reihaneh,, Nasr, Engy,, Li, Huanyu,, Trojahn, Cássia,, Hitzler, Pascal,, Huschka, Martin,, Jiménez-Ruiz, Ernesto,, Abd Nikooie Pour, Mina,, Portisch, Jan,, Pesquita, Catia,, Saveta, Tzanina,, Splendiani, Andrea,, Zamazal, Ondrej,, Faria, Daniel,, Algergawy, Alsayed,, Michel, Franck,, Karam, Naouel,   +31 more
core  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Ontology Alignment Quality

, 2011
Recently semantic web technologies, such as ontologies, have been proposed as key enablers for integrating heterogeneous data schemas in business and governmental systems.
John Krogstie, Csaba Veres, Jennifer Sampson   +2 more
core   +1 more source

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Results of the Ontology Alignment Evaluation Initiative 2021 [Elektronisk resurs]

, 2021
The Ontology Alignment Evaluation Initiative (OAEI) aims at comparing ontology matching systems on precisely defined test cases. These test cases can be based on ontologies of different levels of complexity and use different evaluation modalities (e.g ...
Fundulaki, Irini,, Laadhar, Amir,, Li, Ying,, Paulheim, Heiko,, Zhou, Lu,, Harrow, Ian,, Hertling, Sven,, Roussey, Catherine,, Amardeilh, Florence,, Trojahn, Cassia,, Shvaiko, Pavel,, Yaman, Beyza,, Fallatah, Omaima,, Ibanescu, Liliana,, Lambrix, Patrick,, Amini, Reihaneh,, Nasr, Engy,, Li, Huanyu,, Jimenez-Ruiz, Ernesto,, Hitzler, Pascal,, Huschka, Martin,, Abd Nikooie Pour, Mina,, Portisch, Jan,, Pesquita, Catia,, Vatascinova, Jana,, Saveta, Tzanina,, Splendiani, Andrea,, Zamazal, Ondrej,, Faria, Daniel,, Algergawy, Alsayed,, Michel, Franck,, Karam, Naouel,   +31 more
core  

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

align++ - A Heuristic-based Method for Approximating the Mismatch-at-Risk in Schema-based Ontology Alignment

, 2010
Frequently, ontologies based on the same domain are similar but also have many differences, which are known as heterogeneity. The alignment of entities which are not meant to be used in the same context, or which follow different modeling conventions ...
Schandl, Bernhard, Lanzenberger, Monika, Mazak, Alexandra   +2 more
core   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Ontology Alignment through Argumentation.

, 2012
Currently, the majority of matchers are able to establish simple correspondences between entities, but are not able to provide complex alignments. Furthermore, the resulting alignments do not contain additional information on how they were extracted and formed. Not only it becomes hard to debug the alignment results, but it is also difficult to justify
Luz, Nuno, Silva, Nuno, Maio, Paulo, Novais, Paulo   +3 more
openaire   +2 more sources

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source