Results 141 to 150 of about 176,433 (328)

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Breaking-down the Ontology Alignment Task with a Lexical Index and Neural Embeddings [PDF]

Large ontologies still pose serious challenges to state-of-the-art ontology alignment systems. In the paper we present an approach that combines a lexical index, a neural embedding model and locality modules to effectively divide an input ontology ...
Agibetov, A., Cross, V., Jimenez-Ruiz, E., Samwald, M.   +3 more
core  

Damage Microenvironment Guided Responsive Smart Hydrogel Design for Self‐Regenerative Repair in Chronic Wound Healing

Advanced Materials Interfaces, EarlyView.
Chronic wounds remain a major therapeutic challenge, with VEGF applications hindered by rapid degradation and systemic side effects. Here, a dual‐responsive chitosan–gelatin hydrogel is reported, functionalized with dopamine, glutathione, and MMP‐sensitive motifs, enabling spatiotemporally controlled VEGF release and enhanced biocompatibility, thereby ...
Zhenghui Xiong, Guangzheng Han, Kai Zheng, Yin Gong, Yida Chen, Zili Ge   +5 more
wiley   +1 more source

Advanced Ceramics in Aerospace and Defense: The Interrelationship between Traditional and Additive Manufacturing Approaches

Advanced Materials Technologies, EarlyView.
Additive manufacturing revolutionizes production by enabling on‐demand, customized, and sustainable manufacturing with streamlined supply chains. While metal and polymer AM are well‐established, advanced ceramic AM is rapidly emerging, overcoming traditional material challenges.
Kateryna Oleksandrivna Shvydyuk, Senentxu Lanceros‐Mendez, Abílio Pereira Silva   +2 more
wiley   +1 more source

Ontology alignment using relative entropy for semantic uncertainty analysis [PDF]

, 2010
Erik Blasch, Eric Charles Henri Dorion, Pierre Valin, Éloi Bossé   +3 more
openalex   +1 more source

CCL5hi Macrophages Interact with CD8+ T Cells and Potentiate Responsiveness to PD‐1 Blockade Plus Chemotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study has characterized a functionally distinct macrophage subset, termed CCL5hi macrophages, and elucidated the underlying mechanisms of a regulatory feedback loop that interconnects IFN‐γ, CCL5hi macrophages, and CD8+ T cells within the TME of ESCC undergoing immunochemotherapy.
Yuanzhen Ma, Xiaodong Su, Tingting Zeng, Chunlian Zhou, Guozhen Yang, Zengfei Xia, Chufeng Zeng, Jiarong Zhan, Xin‐Yuan Guan, Xu Zhang, Yan Li   +10 more
wiley   +1 more source

Contextual Ontology Alignment of LOD with an Upper Ontology: A Case Study with Proton [PDF]

, 2011
Prateek Jain, Peter Z. Yeh, Kunal Verma, Reymonrod G. Vasquez, Mariana Damova, Pascal Hitzler, Amit Sheth   +6 more
openalex   +1 more source

Excessive DNA Double‐Strand Breaks–Associated 3D Genome Reorganization Contributes to Neural Tube Defects with Folate Deficiency

Advanced Science, EarlyView.
Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang, Lin Lin, Jianting Li, Caihua Li, Shengjun Liang, Xuemei Bai, Fang Wang, Yihua Bao, Dan Guo, Xiaochen Bo, Hao Li, Hebing Chen, Qiu Xie   +12 more
wiley   +1 more source

Living with the Semantic Gap: Experiences and remedies in the context of medical imaging

, 2006
Semantic annotation of images is a key concern for the newly emerged applications of semantic multimedia. Machine processable descriptions of images make it possible to automate a variety of tasks from search and discovery to composition and collage of ...
Dasmahapatra, Srinandan, Dupplaw, David, Hu, Bo, Kalfoglou, Yannis, Lewis, Paul, Shadbolt, Nigel   +5 more
core  

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source