Results 51 to 60 of about 1,055,752 (313)

An Ontology-Based Method for Semantic Integration of Business Components

, 2011
Building new business information systems from reusable components is today an approach widely adopted and used. Using this approach in analysis and design phases presents a great interest and requires the use of a particular class of components called ...
Elasri, Hicham, Kzaz, Larbi, Sekkaki, Abderrahim   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Alignment of ICNP® 2.0 Ontology and a proposed INCP® Brazilian Ontology

Revista Latino-Americana de Enfermagem, 2014
OBJECTIVE: to align the International Classification for Nursing Practice (ICNP®) Version 2.0 ontology and a proposed INCP® Brazilian Ontology.METHOD: document-based, exploratory and descriptive study, the empirical basis of which was provided by the ...
Carina Maris Gaspar Carvalho, Marcia Regina Cubas, Andreia Malucelli, Maria Miriam Lima da Nóbrega   +3 more
doaj   +1 more source

Ontology Alignment: An annotated Bibliography [PDF]

, 2005
Ontology mapping, alignment, and translation has been an active research component of the general research on semantic integration and interoperability. In our talk, we gave our own classification of different topics in this research.
Mapping and Translation, Noy, Natasha, Stuckenschmidt, Heiner   +2 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Matching biomedical ontologies through compact differential evolution algorithm

Systems Science & Control Engineering, 2019
Although biomedical ontologies have been widely used in the life science domain, the heterogeneous problem among biomedical ontologies hampers their inter-operability.
Xingsi Xue, Junfeng Chen
doaj   +1 more source

Review and Alignment of Domain-Level Ontologies for Materials Science

IEEE Access, 2023
The growing complexity and interdisciplinary nature of Materials Science research demand efficient data management and exchange through structured knowledge representation.
Anne De Baas, Pierluigi Del Nostro, Jesper Friis, Emanuele Ghedini, Gerhard Goldbeck, Ilaria Maria Paponetti, Andrea Pozzi, Arkopaul Sarkar, Lan Yang, Francesco Antonio Zaccarini, Daniele Toti   +10 more
doaj   +1 more source

Ontological quality control in large-scale, applied ontology matching [PDF]

, 2013
To date, large-scale applied ontology mapping has relied greatly on label matching and other relatively simple syntactic features. In search of more holistic and accurate alignment, we offer a suite of partially overlapping ontology mapping heuristics ...
Legg, Catherine, Sarjant, Samuel
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source