Results 61 to 70 of about 689,318 (241)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

The Information-Flow Approach to Ontology-Based Semantic Integration

, 2010
In this article we argue for the lack of formal foundations for ontology-based semantic alignment. We analyse and formalise the basic notions of semantic matching and alignment and we situate them in the context of ontology-based alignment in open-ended ...
Kalfoglou, Yannis, Schorlemmer, Marco
core   +1 more source

Towards valid and reusable reference alignments — ten basic quality checks for ontology alignments and their application to three different reference data sets

Journal of Biomedical Semantics, 2012
Identifying relationships between hitherto unrelated entities in different ontologies is the key task of ontology alignment. An alignment is either manually created by domain experts or automatically by an alignment system.
Beisswanger Elena, Hahn Udo
doaj   +1 more source

Review and Alignment of Domain-Level Ontologies for Materials Science

IEEE Access, 2023
The growing complexity and interdisciplinary nature of Materials Science research demand efficient data management and exchange through structured knowledge representation.
Anne De Baas, Pierluigi Del Nostro, Jesper Friis, Emanuele Ghedini, Gerhard Goldbeck, Ilaria Maria Paponetti, Andrea Pozzi, Arkopaul Sarkar, Lan Yang, Francesco Antonio Zaccarini, Daniele Toti   +10 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Argumentation over Ontology Correspondences in MAS [PDF]

, 2007
In order to support semantic interoperation in open environments, where agents can dynamically join or leave and no prior assumption can be made on the ontologies to align, the different agents involved need to agree on the semantics of the terms used ...
Payne, Terry R., Euzenat, Jerome, Tamma, Valentina, Laera, Loredana, Bench-Capon, Trevor, Blacoe, Ian   +5 more
core   +2 more sources

An Industry-Ready Machine Learning Ontology

Applied Sciences
This article presents an industry-ready ontology for the machine learning domain, which is named “ML Ontology”. While based on lightweight modelling languages, ML ontology provides novel features including built-in queries and quality assurance, as well ...
Bernhard G. Humm
doaj   +1 more source

Alignment of ICNP® 2.0 Ontology and a proposed INCP® Brazilian Ontology

Revista Latino-Americana de Enfermagem, 2014
OBJECTIVE: to align the International Classification for Nursing Practice (ICNP®) Version 2.0 ontology and a proposed INCP® Brazilian Ontology.METHOD: document-based, exploratory and descriptive study, the empirical basis of which was provided by the ...
Carina Maris Gaspar Carvalho, Marcia Regina Cubas, Andreia Malucelli, Maria Miriam Lima da Nóbrega   +3 more
doaj   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

POAF: Portable Ontology Aligned Fragments

, 2008
In today's semantic web, ontology fragmentation and modularization are considered as important tasks due to the size and complexity of prime ontologies.
Kalfoglou, Yannis, Braines, Dave, Smart, Paul R, Shadbolt, Nigel   +3 more
core   +1 more source