Results 81 to 90 of about 1,055,752 (313)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Ontology Matching with Knowledge Rules

open access: yes, 2015
Ontology matching is the process of automatically determining the semantic equivalences between the concepts of two ontologies. Most ontology matching algorithms are based on two types of strategies: terminology-based strategies, which align concepts ...
Dou, Dejing   +2 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Bayesian Evaluation and Comparison of Ontology Alignment Systems

open access: yesIEEE Access, 2019
Ontology alignment systems are evaluated by various performance scores, which are usually computed by a ratio related directly to the frequency of the true positives.
Majid Mohammadi
doaj   +1 more source

An API for Ontology Alignment [PDF]

open access: yes, 2004
Ontologies are seen as the solution to data heterogeneity on the web. However, the available ontologies are themselves source of heterogeneity. This can be overcome by aligning ontologies, or finding the correspondence between their components. These alignments deserve to be treated as objects: they can be referenced on the web as such, be completed by
openaire   +2 more sources

Ontology Alignment using Stable Matching

open access: yesInternational Conference on Knowledge-Based Intelligent Information & Engineering Systems, 2019
Ontology matching is a solution to the problem of semantic heterogeneity in the integration and sharing of information. It consists in establishing mappings between entities which semantically belong to different ontologies.
Imene Ouali   +3 more
semanticscholar   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

New approaches to the ontology alignment and identity resolution problems [PDF]

open access: yesComputer Science Journal of Moldova, 2014
This paper describes approaches to the vocabulary normalization and identity resolution problems arising during the use of the LOD datasets to populate the content of scholarly knowledge bases.
Zinaida Apanovich, Alexander Marchuk
doaj  

On partitioning for ontology alignment [PDF]

open access: yes, 2017
On Partitioning for Ontology Alignment?Sunny Pereira1, Valerie Cross1, Ernesto Jiménez-Ruiz21Miami University, Oxford, OH 45056, United States2University of Oslo, Norway1 IntroductionOntology Alignment (OA) is the process of determining the mappings ...
Cross, V., Jimenez-Ruiz, E., Pereira, S.
core  

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