Results 81 to 90 of about 689,318 (241)
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
New approaches to the ontology alignment and identity resolution problems [PDF]
Computer Science Journal of Moldova, 2014 This paper describes approaches to the vocabulary normalization and identity resolution problems arising during the use of the LOD datasets to populate the content of scholarly knowledge bases.
Zinaida Apanovich, Alexander Marchuk
doaj
On the similarity relation within fuzzy ontology components [PDF]
, 2005 Ontology reuse is an important research issue. Ontology merging, integration, mapping, alignment and versioning are some of its subprocesses. A considerable research work has been conducted on them.
Bejaoui, Lotfi +2 more
core
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Biomedical ontology alignment: an approach based on representation learning
Journal of Biomedical Semantics, 2018 Background While representation learning techniques have shown great promise in application to a number of different NLP tasks, they have had little impact on the problem of ontology matching.
Prodromos Kolyvakis +3 more
doaj +1 more source
Bootstrapping ontology alignment methods with APFEL [PDF]
Special interest tracks and posters of the 14th international conference on World Wide Web - WWW '05, 2005 Ontology alignment is a prerequisite in order to allow for interoperation between different ontologies and many alignment strategies have been proposed to facilitate the alignment task by (semi-)automatic means. Due to the complexity of the alignment task, manually defined methods for (semi-)automatic alignment rarely constitute an optimal ...
Marc Ehrig, Steffen Staab, York Sure
openaire +2 more sources
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Complex Systems Informatics and Modeling Quarterly, 2016 Achieving interoperability, i.e. creating identity federations between different Electronic identities (eID) systems, has gained relevance throughout the past years.
Walter Priesnitz Filho +2 more
doaj +1 more source