Results 91 to 100 of about 246,657 (302)

Dynamic sub-ontology evolution for traditional Chinese medicine web ontology

Journal of Biomedical Informatics, 2008
As a form of important domain knowledge, large-scale ontologies play a critical role in building a large variety of knowledge-based systems. To overcome the problem of semantic heterogeneity and encode domain knowledge in reusable format, a large-scale and well-defined ontology is also required in the traditional Chinese medicine discipline.
Mao, Yuxin, Wu, Zhaohui, Tian, Wenya, Jiang, Xiaohong, Cheung, William K.   +4 more
openaire   +2 more sources

Grid Metadata Lifetime Control in ActOn [PDF]

, 2008
In the Semantic Grid, metadata, as first class citizens, should be maintained up to-date in a cost-effective manner. This includes maxi missing the automation of different aspects of the metadata lifecycle, managing the evolution and change of metadata in
Corcho, Oscar, Dikaiakos, M., Goble, C., Sakellariou, R., Xing, W.   +4 more
core   +1 more source

Ontological support for the evolution of future services oriented architectures [PDF]

, 2014
Services Oriented Architectures (SOA) have emerged as a useful framework for developing interoperable, large-scale systems, typically implemented using the Web Services (WS) standards.
Bagui, Sikha, El-Sheikh, Eman, Fang, Xingang, Gonen, Bilal, Wilde, Norman, Zimmermann, Alfred   +5 more
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

A Methodological Framework for Runtime Ontology Evolution in Dynamic Environments

Applied Sciences
Intelligent systems operating in real-world environments are often required to make decisions in contexts that are only partially known at design time. In such scenarios, the assumption of a static and fully specified knowledge base becomes unrealistic ...
Valeria Seidita, Lucrezia Mosca, Antonio Chella   +2 more
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Linking Open Descriptions of Social Events (LODSE): A New Ontology for Social Event Classification

Information, 2018
The digital era has brought a number of significant changes in the world of communications. Although technological evolution has allowed the creation of new social event platforms to disclose events, it is still difficult to know what is happening around
Marcelo Rodrigues, Rodrigo Rocha Silva, Jorge Bernardino   +2 more
doaj   +1 more source

Change Management: The Core Task of Ontology Versioning and Evolution

, 2005
Change management as a key issue in ontology versioning and evolution is still not fully addressed, which to some extent forms a barrier against the smooth process of ontology evolution.
Alani, Harith, Liang, Yaozhong, Shadbolt, Nigel   +2 more
core  

Ontology-based domain modelling for consistent content change management [PDF]

, 2010
Ontology-based modelling of multi-formatted software application content is a challenging area in content management. When the number of software content unit is huge and in continuous process of change, content change management is important.
Abgaz, Yalemisew, Javed, Muhammad, Pahl, Claus   +2 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source