Results 51 to 60 of about 54,469 (259)
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
A Community Network Ontology for Participatory Collaboration Mapping: Towards Collective Impact
Information, 2018 Addressing societal wicked problems requires collaboration across many different community networks. In order for community networks to scale up their collaboration and increase their collective impact, they require a process of inter-communal ...
Aldo de Moor
doaj +1 more source
Harvesting online ontologies for ontology evolution [PDF]
, 2011 Ontologies need to evolve to keep their domain representation adequate. However, the process of identifying new domain changes, and applying them to the ontology is tedious and time-consuming. Our hypothesis is that online ontologies can provide background knowledge to decrease user efforts during ontology evolution, by integrating new domain concepts ...
openaire +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
FEBS Open Bio, EarlyView.Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Interactive Cross-Lingual Ontology Matching
IEEE Access, 2019 Recently, with the growing number of ontologies defined in different languages, to bridge the semantic gaps between them, it is necessary to identify the correspondences between their heterogeneous entities, so-called cross-lingual ontology matching. Due
Junfeng Chen +3 more
doaj +1 more source
Estimation of the Genetic Substitution Rate of Hanwoo and Holstein Cattle Using Whole Genome Sequencing Data [PDF]
Genomics & Informatics, 2018 Despite the importance of mutation rate, some difficulties exist in estimating it. Next-generation sequencing (NGS) data yields large numbers of single-nucleotide polymorphisms, which can make it feasible to estimate substitution rates.
Young-Sup Lee, Donghyun Shin
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
FEBS Open Bio, EarlyView.Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Capture and Process Differences Between Ontologies
IEEE AccessThe Ontology Development Tracker (OnDeT) has been developed to facilitate the computation and interactive exploration of differences between multiple versions of a Git-hosted ontology throughout its temporal evolution.
Felix Engel, Mark Vanin, Nenad Krdzavac
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source