Results 61 to 70 of about 103,296 (308)

Comparing human and automatic thesaurus mapping approaches in the agricultural domain [PDF]

, 2008
Knowledge organization systems (KOS), like thesauri and other controlled vocabularies, are used to provide subject access to information systems across the web.
Keizer, Johannes, Lauser, B., Caracciolo, C., van Hage, W.R., Johannsen, G., Johannsen, Gudrun, Caracciolo, Caterina, Hage, W.R. van, Mayr, P., Lauser, Boris, Hage, Willem Robert van, Keizer, J., van Hage, Willem Robert, Mayr, Philipp   +13 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Detecting and Correcting Conservativity Principle Violations in Ontology-to-Ontology Mappings [PDF]

, 2014
In order to enable interoperability between ontology-based systems, ontology matching techniques have been proposed. However, when the generated mappings suffer from logical flaws, their usefulness may be diminished. In this paper we present an approximate method to detect and correct violations to the so-called conservativity principle where novel ...
Alessandro Solimando, Ernesto Jiménez-Ruiz, Giovanna Guerrini   +2 more
openaire   +5 more sources

Results from experiments in ontology learning including evaluation and recommendation [PDF]

, 2007
This document describes the Ontology Learning experiments we performed in order to recommend a set of ontology learning techniques to enhance the ontology engineering process in the fisheries domain in place at FAO. Experiments have been conceived in the
Caracciolo, Caterina, D'Aquin, Mathieu, Sabou, Marta, Voelker, Johanna, Peters, Wim   +4 more
core  

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

The use of ontologies for effective knowledge modelling and information retrieval

Applied Computing and Informatics, 2018
The dramatic increase in the use of knowledge discovery applications requires end users to write complex database search requests to retrieve information.
Kamran Munir, M. Sheraz Anjum
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Automating Ontology Mapping in IT Service Management: A DOLCE and ITSMO Integration

Data Science Journal
Background: Ontologies and knowledge graphs have become critical for structuring data into machine-interpretable knowledge, especially in dynamic domains like IT service management (ITSM). Traditional ontology engineering relies heavily on domain experts,
Andrey Khalov, Olga Ataeva
doaj   +1 more source

Ontology-Based Personalized Course Recommendation Framework

IEEE Access, 2019
Choosing a higher education course at university is not an easy task for students. A wide range of courses are offered by the individual universities whose delivery mode and entry requirements differ.
Mohammed E. Ibrahim, Yanyan Yang, David L. Ndzi, Guangguang Yang, Murtadha Al-Maliki   +4 more
doaj   +1 more source