Results 131 to 140 of about 1,176,214 (330)

Results of the Ontology Alignment Evaluation Initiative 2014

, 2014
Ontology matching consists of finding correspondences between se-mantically related entities of two ontologies. OAEI campaigns aim at comparingontology matching systems on precisely defined test cases.
Paulheim, Heiko,, Kempf, Andreas,, Solimando, Alessandro,, Dragisic, Zlatan,, Trojahn, Cassia,, Euzenat, Jerome,, Shvaiko, Pavel,, Zamazal, Ondrej,, Ritze, Dominique,, Lambrix, Patrick,, Ferrara, Alfio,, Ivanova, Valentina,, Montanelli, Stefano,, Faria, Daniel,, Cuenca Grau, Bernardo,, Granada, Roger,, Eckert, Kai,, Jimenez-Ruiz, Ernesto,   +17 more
core  

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Institutionalising Ontology-Based Semantic Integration

, 2007
We address what is still a scarcity of general mathematical foundations for ontology-based semantic integration underlying current knowledge engineering methodologies in decentralised and distributed environments. After recalling the first-order ontology-
Kalfoglou, Yannis, Schorlemmer, Marco, Marco Schorlemmer, Yannis Kalfoglou   +3 more
core  

TRMT6‐Mediated m1A Modification of CDK9 mRNA Is a Dual‐Pronged Pathogenic Driver for HBV‐Related Hepatocellular Carcinoma

Advanced Science, EarlyView.
TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang, Dandan Zong, Rui Liu, Yubo Wang, Qingqing Gu, Yao Yao, Wenfang Zheng, Mengmeng Yuan, Simeng Wang, Rongrong Cui, Daxu Li, Siwen Dang, Peng Hou   +12 more
wiley   +1 more source

Results of the Ontology Alignment Evaluation Initiative 2023

97139The Ontology Alignment Evaluation Initiative (OAEI) aims at comparing ontology matching systems on precisely defined test cases. These test cases can be based on ontologies of different levels of complexity and use different evaluation modalities ...
Lambrix, Patrick, Fallatah, Omaima, Monnin, Pierre, Coulet, Adrien, Ibanescu, Liliana, Hertling, Sven, Wu, Mingfang, Li, Huanyu, Nasr, Engy, Faria, Daniel, He, Yuan, Algergawy, Alsayed, Jain, Sarika, Jimenez-Ruiz, Ernesto, Hang, Dong, Trojahn, Cassia, Karam, Naouel, Horrocks, Ian, Shvaiko, Pavel, Saveta, Tzanina, Buche, Patrice, Fundulaki, Irini, Paulheim, Heiko, Cufi, Julien, Huschka, Martin, Yaman, Beyza, Zamazal, Ondrej, Vatascinova, Jana, Abd Nikooie Pour, Mina, Zhou, Lu, Li, Ying, Castro, Leyla J., Pesquita, Catia, Chen, Jiaoyan, Sousa, Guilherme   +34 more
core   +1 more source

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Uncertainty in Automated Ontology Matching: Lessons from an Empirical Evaluation

Applied Sciences
Data integration is considered a classic research field and a pressing need within the information science community. Ontologies play a critical role in such processes by providing well-consolidated support to link and semantically integrate datasets via
Inès Osman, Salvatore Flavio Pileggi, Sadok Ben Yahia   +2 more
doaj   +1 more source

DOT1L Drives Endothelial‐to‐Mesenchymal Transition and Fibrotic Vascular Remodeling via H3K79 Methylation

Advanced Science, EarlyView.
DOT1L as a central epigenetic regulator of EndoMT and pulmonary fibrosis. Acting as an early epigenetic switch, it translates TGFβ–SMAD signaling into H3K79me2‐mediated chromatin remodeling, selectively activates fibrosis‐related genes, and primes ECs for rapid mesenchymal transition.
Yaofeng Wang, Xing Peng, Jingjing Chen, Yun Zhang, Tinghong Zhang, Jingyuan Zhang, Jiaying Fan, Hui Zheng, Qiaoyuan Liu, Zhimin Song, Zhan‐Peng Huang, Shu Meng   +11 more
wiley   +1 more source

Ontology Matching

, 2005
No abstract available.
Shvaiko, Pavel, Euzenat, Jérôme
openaire   +2 more sources