Results 41 to 50 of about 38,633 (261)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Tackling the challenges of matching biomedical ontologies

Journal of Biomedical Semantics, 2018
Background Biomedical ontologies pose several challenges to ontology matching due both to the complexity of the biomedical domain and to the characteristics of the ontologies themselves.
Daniel Faria, Catia Pesquita, Isabela Mott, Catarina Martins, Francisco M. Couto, Isabel F. Cruz   +5 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Improving Ontology Matching Using Application Requirements for Segmenting Ontologies [PDF]

Journal of Universal Computer Science, 2019
Ontology matching is concerned with finding relations between elements of different ontologies. In large-scale settings, some significant challenges arise, such as how to achieve a reduction in the time it takes to perform matching and how to improve the
Diego Pessoa, Ana Salgado, Bernadette Lóscio   +2 more
doaj   +3 more sources

Matching Biomedical Ontologies via a Hybrid Graph Attention Network

Frontiers in Genetics, 2022
Biomedical ontologies have been used extensively to formally define and organize biomedical terminologies, and these ontologies are typically manually created by biomedical experts. With more biomedical ontologies being built independently, matching them
Peng Wang, Peng Wang, Yunyan Hu
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

A Compact Flow Regime Algorithm for Improving the Efficiency of Metaheuristics-Based Ontology Matching System

IEEE Access
Ontology matching is a key technology for solving the problem of semantic heterogeneity between ontologies. In past years, scholars have proposed many approaches committed to improve the quality of ontology matching.
Zhaoming Lv
doaj   +1 more source

Semantic matching of cloud resource service for user product design requirement

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
Under the cloud manufacturing (CMfg) environment, a multilayer semantic matching model of design requirement and cloud service resource based on ontology was proposed to guarantee the rapid and accurate matching of resource services to meet the cloud ...
Minghai YUAN, Chao SUN, XianXian CAI, Zhuo ZHOU, Wenbin GU   +4 more
doaj   +1 more source

Advances in Ontology Matching [PDF]

, 2008
n ...
Gal, Avigdor, Shvaiko, Pavel
openaire   +2 more sources