Results 61 to 70 of about 821,533 (281)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Effective Ontology Matching in High-Performance Computing Environments

open access: yes, 2009
Extending complex information structures by means of ontology matching is of high interest for a number of tasks solved in the semantic web. The main motivation behind this work is that the procedure of ontology matching requires a robust and scalable ...
Cheptsov, Alexey, Tenschert, Axel
core   +1 more source

A Flexible System for Ontology Matching [PDF]

open access: yes, 2012
Most of solutions provided by current ontology matching tools lack flexibility and extensibility namely for adding new matchers and dealing with users' requirements. In this paper, we present a system YAM++, which supports self-configuration, flexibility and extensibility in combining individual matchers.
Ngo, Duy Hoa   +2 more
openaire   +3 more sources

Ontology-based composition and matching for dynamic cloud service coordination [PDF]

open access: yes, 2012
Recent cross-organisational software service offerings, such as cloud computing, create higher integration needs. In particular, services are combined through brokers and mediators, solutions to allow individual services to collaborate and their ...
Yapa Bandara, Kosala   +3 more
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

A Compact Flow Regime Algorithm for Improving the Efficiency of Metaheuristics-Based Ontology Matching System

open access: yesIEEE Access
Ontology matching is a key technology for solving the problem of semantic heterogeneity between ontologies. In past years, scholars have proposed many approaches committed to improve the quality of ontology matching.
Zhaoming Lv
doaj   +1 more source

Semantic matching of cloud resource service for user product design requirement

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
Under the cloud manufacturing (CMfg) environment, a multilayer semantic matching model of design requirement and cloud service resource based on ontology was proposed to guarantee the rapid and accurate matching of resource services to meet the cloud ...
Minghai YUAN   +4 more
doaj   +1 more source

Results of the ontology alignment evaluation initiative 2020

open access: yes, 2022
92138The Ontology Alignment Evaluation Initiative (OAEI) aims at com-paring ontology matching systems on precisely defined test cases. These testcases can be based on ontologies of different levels of complexity and use different evaluation modalities (e.
Lambrix, Patrick   +26 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Ontology matching for patent classification

open access: yes, 2022
3748Interdisciplinary research and development projects in medical engineering benefit from well selected collaboration partners. The process of finding such partners from often unfamiliar fields is difficult, but can be supported by an expert profile ...
Hai, R.   +3 more
core   +1 more source

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