Results 61 to 70 of about 134,903 (295)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ontology-based composition and matching for dynamic cloud service coordination [PDF]

open access: yes, 2012
Recent cross-organisational software service offerings, such as cloud computing, create higher integration needs. In particular, services are combined through brokers and mediators, solutions to allow individual services to collaborate and their ...
Gacitua-Decar, Veronica   +3 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

A Compact Flow Regime Algorithm for Improving the Efficiency of Metaheuristics-Based Ontology Matching System

open access: yesIEEE Access
Ontology matching is a key technology for solving the problem of semantic heterogeneity between ontologies. In past years, scholars have proposed many approaches committed to improve the quality of ontology matching.
Zhaoming Lv
doaj   +1 more source

Semantic matching of cloud resource service for user product design requirement

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
Under the cloud manufacturing (CMfg) environment, a multilayer semantic matching model of design requirement and cloud service resource based on ontology was proposed to guarantee the rapid and accurate matching of resource services to meet the cloud ...
Minghai YUAN   +4 more
doaj   +1 more source

A conceptual architecture for semantic web services development and deployment [PDF]

open access: yes, 2004
Several extensions of the Web Services Framework (WSF) have been proposed. The combination with Semantic Web technologies introduces a notion of semantics, which can enhance scalability through automation.
Pahl, Claus
core   +2 more sources

Advances in Ontology Matching [PDF]

open access: yes, 2008
n ...
Gal, Avigdor, Shvaiko, Pavel
openaire   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Methodological Guidelines for Matching Ontologies

open access: yes, 2011
Finding alignments between ontologies is a very important operation for ontology engineering. It allows for establishing links between ontologies, either to integrate them in an application or to relate developed ontologies to context. It is even more critical for networked ontologies.
Euzenat, Jérôme, Le Duc, Chan
openaire   +2 more sources

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