Results 1 to 10 of about 60,734 (100)

Isolation and in vitro Culture of Mouse Oocytes

open access: yesBio-Protocol, 2021
Females are endowed at birth with a fixed reserve of oocytes, which declines both in quantity and quality with advancing age. Understanding the molecular mechanisms regulating oocyte quality is crucial for improving the chances of pregnancy success in ...
Jessica Greaney   +3 more
doaj   +1 more source

Lipid Metabolism Was Associated With Oocyte in vitro Maturation in Women With Polycystic Ovarian Syndrome Undergoing Unstimulated Natural Cycle

open access: yesFrontiers in Cell and Developmental Biology, 2021
ObjectiveHyperlipidemia are common polycystic ovarian syndrome (PCOS)-related metabolic dysfunctions and can adversely affect assisted reproductive technology (ART) outcomes in controlled ovarian hyperstimulation (COH) cycles. The objective of this study
Tao Liu   +74 more
doaj   +1 more source

An Eight Year Experience of Autologous Oocyte Vitrification for Infertile Patients Owing to Unavailability of Sperm on Oocyte Retrieval Day

open access: yesFrontiers in Medicine, 2021
Objective: The objective of this study was to provide a descriptive analysis of the clinical outcomes achieved in oocyte vitrification in cases where sperm was unavailable on oocyte retrieval day, and to identify predictors of oocyte survival.Methods ...
Xiao Fu   +22 more
doaj   +1 more source

A PP2A-B56—Centered View on Metaphase-to-Anaphase Transition in Mouse Oocyte Meiosis I

open access: yesCells, 2020
Meiosis is required to reduce to haploid the diploid genome content of a cell, generating gametes—oocytes and sperm—with the correct number of chromosomes.
Leonor Keating   +2 more
doaj   +1 more source

The Presence of Immature GV− Stage Oocytes during IVF/ICSI Is a Marker of Poor Oocyte Quality: A Pilot Study

open access: yesMedical Sciences, 2020
Here we investigate whether the presence of germinal vesicle-stage oocytes (GV− oocytes) reflects poor oocyte developmental competence (or quality).
Pia Astbury   +5 more
doaj   +1 more source

Is It Possible to Expand Oocyte Donors by Decreasing Number of Oocytes for Own Use? Insights From a Large Single-Center Study

open access: yesFrontiers in Endocrinology, 2021
BackgroundCurrently, in China, only women undergoing in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) cycles can donate oocytes to others, but at least 15 oocytes must be kept for their own treatment.
Zhiqin Bu   +3 more
doaj   +1 more source

Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

open access: yesNature Communications, 2020
Meiotic cell division in oocytes is asymmetric and requires microtubule spindle migration after anaphase-onset. Here, the authors show that Nampt, an enzyme of the Nicotinamide adenine dinucleotide (NAD) biosynthetic pathway, contributes to post-anaphase
Zhe Wei   +3 more
doaj   +1 more source

The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization

open access: yesCells, 2021
Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the distribution of location. CCs are supporting cells of the oocyte that protect
Bongkoch Turathum   +2 more
doaj   +1 more source

Oocyte Competence Biomarkers Associated With Oocyte Maturation: A Review

open access: yesFrontiers in Cell and Developmental Biology, 2021
Oocyte developmental competence is one of the determining factors that influence the outcomes of an IVF cycle regarding the ability of a female gamete to reach maturation, be fertilized, and uphold an embryonic development up until the blastocyst stage ...
Batara Sirait   +9 more
doaj   +1 more source

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

open access: yesNature Communications, 2018
Female meiotic divisions are asymmetric with the formation of large oocytes and small polar bodies, thought to result from cortical spindle placement before anaphase.
Zhe Wei   +3 more
doaj   +1 more source

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