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Oocyte cryopreservation review: outcomes of medical oocyte cryopreservation and planned oocyte cryopreservation [PDF]

open access: yesReproductive Biology and Endocrinology, 2022
Background The utilization of oocyte cryopreservation (OC) has become popularized with increasing numbers of reproductive-aged patients desiring to maintain fertility for future family building.
Zachary Walker   +2 more
doaj   +3 more sources

The Xenopus Oocyte System: Molecular Dynamics of Maturation, Fertilization, and Post-Ovulatory Fate [PDF]

open access: yesBiomolecules
The Xenopus oocyte has long served as a versatile and powerful model for dissecting the molecular underpinnings of reproductive and developmental processes. Its large size, manipulability, and well-characterized cell cycle states have enabled generations
Ken-Ichi Sato
doaj   +2 more sources

EFNA5 as an Oocyte-Derived Factor Enhances Developmental Competence by Modulating Oxidative Stress, Inflammation, and Apoptosis During In Vitro Maturation [PDF]

open access: yesAntioxidants
In vitro maturation (IVM) of oocytes remains suboptimal due to oxidative stress and disrupted cumulus–oocyte communication. Oocyte-derived factors (ODFs) are key mediators of this crosstalk and crucial for oocyte competence.
Xingyuan Liu   +8 more
doaj   +2 more sources

Isolation and in vitro Culture of Mouse Oocytes

open access: yesBio-Protocol, 2021
Females are endowed at birth with a fixed reserve of oocytes, which declines both in quantity and quality with advancing age. Understanding the molecular mechanisms regulating oocyte quality is crucial for improving the chances of pregnancy success in ...
Jessica Greaney   +3 more
doaj   +1 more source

The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development

open access: yesCell Reports, 2022
Summary: Inactivation of cyclin-dependent kinase 1 (Cdk1), controlled by cyclin B1 proteolysis, orders events during mitotic exit. Here, we used a FRET biosensor to study Cdk1 activity while simultaneously monitoring anaphase II and pronuclear (PN ...
Chenxi Zhou, Hayden A. Homer
doaj   +1 more source

Lipid Metabolism Was Associated With Oocyte in vitro Maturation in Women With Polycystic Ovarian Syndrome Undergoing Unstimulated Natural Cycle

open access: yesFrontiers in Cell and Developmental Biology, 2021
ObjectiveHyperlipidemia are common polycystic ovarian syndrome (PCOS)-related metabolic dysfunctions and can adversely affect assisted reproductive technology (ART) outcomes in controlled ovarian hyperstimulation (COH) cycles. The objective of this study
Tao Liu   +74 more
doaj   +1 more source

Oocyte cryopreservation [PDF]

open access: yesHuman Reproduction, 1998
Cryopreservation of human oocytes has been employed with little success in clinical practice, even though it may solve the legal and ethical problems linked to embryo freezing. Various attempts to cryopreserve human oocytes have mostly been unsuccessful, leading to low oocyte survival rates after thawing, and the search for an optimal protocol for ...
R, Fabbri   +8 more
openaire   +2 more sources

A PP2A-B56—Centered View on Metaphase-to-Anaphase Transition in Mouse Oocyte Meiosis I

open access: yesCells, 2020
Meiosis is required to reduce to haploid the diploid genome content of a cell, generating gametes—oocytes and sperm—with the correct number of chromosomes.
Leonor Keating   +2 more
doaj   +1 more source

Is there an optimal timing interval between hCG trigger and oocyte vitrification?

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2022
Objective: Oocyte vitrification has been developed as a promising alternative to slow freezing; however, the clinical outcome is highly operator dependent.
Yu-Wen Weng   +5 more
doaj   +1 more source

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