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The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization

open access: yesCells, 2021
Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the distribution of location. CCs are supporting cells of the oocyte that protect
Bongkoch Turathum   +2 more
doaj   +2 more sources

Oocyte quality and aging

open access: greenJBRA Assisted Reproduction, 2021
It is well known that female reproduction ability decreases during the forth decade of life due to age-related changes in oocyte quality and quantity; although the number of women trying to conceive has today increased remarkably between the ages of 36 ...
Ali Reza Eftekhari Moghadam   +3 more
openalex   +3 more sources

Oocyte cryopreservation review: outcomes of medical oocyte cryopreservation and planned oocyte cryopreservation [PDF]

open access: yesReproductive Biology and Endocrinology, 2022
Background The utilization of oocyte cryopreservation (OC) has become popularized with increasing numbers of reproductive-aged patients desiring to maintain fertility for future family building.
Zachary Walker   +2 more
doaj   +3 more sources

Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

open access: yesNature, 2017
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the ...
Ilya M Flyamer   +2 more
exaly   +2 more sources

The Role of Oocyte Organelles in Determining Developmental Competence

open access: yesBiology, 2017
The ability of an oocyte to undergo successful cytoplasmic and nuclear maturation, fertilization and embryo development is referred to as the oocyte’s quality or developmental competence.
Karen L. Reader   +2 more
doaj   +2 more sources

EFNA5 as an Oocyte-Derived Factor Enhances Developmental Competence by Modulating Oxidative Stress, Inflammation, and Apoptosis During In Vitro Maturation [PDF]

open access: yesAntioxidants
In vitro maturation (IVM) of oocytes remains suboptimal due to oxidative stress and disrupted cumulus–oocyte communication. Oocyte-derived factors (ODFs) are key mediators of this crosstalk and crucial for oocyte competence.
Xingyuan Liu   +8 more
doaj   +2 more sources

Isolation and in vitro Culture of Mouse Oocytes

open access: yesBio-Protocol, 2021
Females are endowed at birth with a fixed reserve of oocytes, which declines both in quantity and quality with advancing age. Understanding the molecular mechanisms regulating oocyte quality is crucial for improving the chances of pregnancy success in ...
Jessica Greaney   +3 more
doaj   +1 more source

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