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The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization

open access: yesCells, 2021
Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the distribution of location. CCs are supporting cells of the oocyte that protect
Bongkoch Turathum   +2 more
doaj   +2 more sources

Oocyte cryopreservation review: outcomes of medical oocyte cryopreservation and planned oocyte cryopreservation [PDF]

open access: yesReproductive Biology and Endocrinology, 2022
Background The utilization of oocyte cryopreservation (OC) has become popularized with increasing numbers of reproductive-aged patients desiring to maintain fertility for future family building.
Zachary Walker   +2 more
doaj   +3 more sources

The Role of Oocyte Organelles in Determining Developmental Competence

open access: yesBiology, 2017
The ability of an oocyte to undergo successful cytoplasmic and nuclear maturation, fertilization and embryo development is referred to as the oocyte’s quality or developmental competence.
Karen L. Reader   +2 more
doaj   +2 more sources

Functional Roles of Src Kinase Activity in Oocyte Maturation and Artificial Egg Activation in Xenopus laevis [PDF]

open access: yesCells
Src family tyrosine kinases regulate oocyte maturation and fertilization in many species, yet their physiological roles in Xenopus laevis (X. laevis) remain incompletely defined. Here, we generated three X. laevis Src (xSrc) constructs with defined point
Ken-ichi Sato, Alexander A. Tokmakov
doaj   +2 more sources

Isolation and in vitro Culture of Mouse Oocytes

open access: yesBio-Protocol, 2021
Females are endowed at birth with a fixed reserve of oocytes, which declines both in quantity and quality with advancing age. Understanding the molecular mechanisms regulating oocyte quality is crucial for improving the chances of pregnancy success in ...
Jessica Greaney   +3 more
doaj   +1 more source

The Role of Mitochondria in Oocyte Maturation

open access: yesCells, 2021
With the nucleus as an exception, mitochondria are the only animal cell organelles containing their own genetic information, called mitochondrial DNA (mtDNA).
A. Kirillova   +3 more
semanticscholar   +1 more source

The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development

open access: yesCell Reports, 2022
Summary: Inactivation of cyclin-dependent kinase 1 (Cdk1), controlled by cyclin B1 proteolysis, orders events during mitotic exit. Here, we used a FRET biosensor to study Cdk1 activity while simultaneously monitoring anaphase II and pronuclear (PN ...
Chenxi Zhou, Hayden A. Homer
doaj   +1 more source

Mitochondria: Their relevance during oocyte ageing

open access: yesAgeing Research Reviews, 2021
The oocyte is recognised as the largest cell in mammalian species and other multicellular organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and mitochondrial architecture is different in oocytes than in somatic cells ...
Jiska van der Reest   +3 more
semanticscholar   +1 more source

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