Results 1 to 10 of about 265,248 (262)

Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition

open access: yesNature, 2017
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the ...
Ilya M Flyamer   +2 more
exaly   +2 more sources

The Function of Cumulus Cells in Oocyte Growth and Maturation and in Subsequent Ovulation and Fertilization

open access: yesCells, 2021
Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the distribution of location. CCs are supporting cells of the oocyte that protect
Bongkoch Turathum, Er-Meng Gao, R. Chian
semanticscholar   +1 more source

The Role of Mitochondria in Oocyte Maturation

open access: yesCells, 2021
With the nucleus as an exception, mitochondria are the only animal cell organelles containing their own genetic information, called mitochondrial DNA (mtDNA).
A. Kirillova   +3 more
semanticscholar   +1 more source

Oocyte cryopreservation: where are we now?

open access: yesHuman Reproduction Update, 2016
Joyce C Harper, Melanie C Davies
exaly   +2 more sources

Mechanisms of Oocyte Maturation and Related Epigenetic Regulation

open access: yesFrontiers in Cell and Developmental Biology, 2021
Meiosis is the basis of sexual reproduction. In female mammals, meiosis of oocytes starts before birth and sustains at the dictyate stage of meiotic prophase I before gonadotropins-induced ovulation happens. Once meiosis gets started, the oocytes undergo
Meina He, Tuo Zhang, Yi Yang, Chao Wang
semanticscholar   +1 more source

Oocyte quality and aging

open access: yesJBRA Assisted Reproduction, 2021
It is well known that female reproduction ability decreases during the forth decade of life due to age-related changes in oocyte quality and quantity; although the number of women trying to conceive has today increased remarkably between the ages of 36 ...
Ali Reza Eftekhari Moghadam   +3 more
semanticscholar   +1 more source

Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development

open access: yesPLoS Genetics, 2018
The N6-methyladenosine (m6A) modification is the most prevalent internal RNA modification in eukaryotes. The majority of m6A sites are found in the last exon and 3’ UTRs.
Seth D. Kasowitz   +8 more
semanticscholar   +1 more source

Sperm proteins SOF1, TMEM95, and SPACA6 are required for sperm−oocyte fusion in mice

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance The sperm−oocyte fusion step is important to transport the male genome into oocytes. So far, IZUMO1 and FIMP have been identified as fusion-related proteins in spermatozoa, but the molecular mechanisms underpinning sperm−oocyte fusion and ...
Taichi Noda   +7 more
semanticscholar   +1 more source

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