Cumulus cells (CCs) originating from undifferentiated granulosa cells (GCs) differentiate in mural granulosa cells (MGCs) and CCs during antrum formation in the follicle by the distribution of location. CCs are supporting cells of the oocyte that protect
Bongkoch Turathum +2 more
doaj +2 more sources
It is well known that female reproduction ability decreases during the forth decade of life due to age-related changes in oocyte quality and quantity; although the number of women trying to conceive has today increased remarkably between the ages of 36 ...
Ali Reza Eftekhari Moghadam +3 more
openalex +3 more sources
Oocyte cryopreservation review: outcomes of medical oocyte cryopreservation and planned oocyte cryopreservation [PDF]
Background The utilization of oocyte cryopreservation (OC) has become popularized with increasing numbers of reproductive-aged patients desiring to maintain fertility for future family building.
Zachary Walker +2 more
doaj +3 more sources
Single-nucleus Hi-C reveals unique chromatin reorganization at oocyte-to-zygote transition
Chromatin is reprogrammed after fertilization to produce a totipotent zygote with the potential to generate a new organism. The maternal genome inherited from the oocyte and the paternal genome provided by sperm coexist as separate haploid nuclei in the ...
Ilya M Flyamer +2 more
exaly +2 more sources
The Role of Oocyte Organelles in Determining Developmental Competence
The ability of an oocyte to undergo successful cytoplasmic and nuclear maturation, fertilization and embryo development is referred to as the oocyte’s quality or developmental competence.
Karen L. Reader +2 more
doaj +2 more sources
EFNA5 as an Oocyte-Derived Factor Enhances Developmental Competence by Modulating Oxidative Stress, Inflammation, and Apoptosis During In Vitro Maturation [PDF]
In vitro maturation (IVM) of oocytes remains suboptimal due to oxidative stress and disrupted cumulus–oocyte communication. Oocyte-derived factors (ODFs) are key mediators of this crosstalk and crucial for oocyte competence.
Xingyuan Liu +8 more
doaj +2 more sources
Regulation of Mammalian Oocyte Meiosis by Intercellular Communication Within the Ovarian Follicle
Laurinda A Jaffe
exaly +2 more sources
The epidermal growth factor network: role in oocyte growth, maturation and developmental competence
D Richani, Robert B Gilchrist
exaly +2 more sources
Isolation and in vitro Culture of Mouse Oocytes
Females are endowed at birth with a fixed reserve of oocytes, which declines both in quantity and quality with advancing age. Understanding the molecular mechanisms regulating oocyte quality is crucial for improving the chances of pregnancy success in ...
Jessica Greaney +3 more
doaj +1 more source
Reciprocal Interactions Between Human GV-Oocytes and Cumulus Cells: Effects on GVBD, ROS Production, and AMPK Expression. [PDF]
Ban Z +4 more
europepmc +2 more sources

