Results 31 to 40 of about 241,792 (308)

Impact of Oxidative Stress on Age-Associated Decline in Oocyte Developmental Competence

open access: yesFrontiers in Endocrinology, 2019
Reproductive capacity in women starts to decline beyond their mid-30s and pregnancies in older women result in higher rates of miscarriage with aneuploidy.
Hiroyuki Sasaki   +7 more
semanticscholar   +1 more source

Obesity Induces Ovarian Inflammation and Reduces Oocyte Quality.

open access: yesReproduction, 2019
In the US, 36.5 percent of women between the ages of 20-39 are obese. This obesity results in not only metabolic disorders including type II diabetes and cardiovascular disease, but also impaired female fertility.
A. Snider, J. Wood
semanticscholar   +1 more source

Impact of Maternal Age on Oocyte and Embryo Competence

open access: yesFrontiers in Endocrinology, 2018
The overall success of human reproduction, either spontaneously or after IVF, is highly dependent upon maternal age. The main reasons for age-related infertility include reduced ovarian reserve and decreased oocyte/embryo competence due to aging insults,
D. Cimadomo   +5 more
semanticscholar   +1 more source

Regulation of fatty acid oxidation in mouse cumulus-oocyte complexes during maturation and modulation by PPAR agonists.

open access: yesPLoS ONE, 2014
Fatty acid oxidation is an important energy source for the oocyte; however, little is known about how this metabolic pathway is regulated in cumulus-oocyte complexes.
Kylie R Dunning   +4 more
doaj   +1 more source

Oocyte, embryo and blastocyst cryopreservation in ART: systematic review and meta-analysis comparing slow-freezing versus vitrification to produce evidence for the development of global guidance

open access: yesHuman Reproduction Update, 2016
BACKGROUND Successful cryopreservation of oocytes and embryos is essential not only to maximize the safety and efficacy of ovarian stimulation cycles in an IVF treatment, but also to enable fertility preservation.
L. Rienzi   +7 more
semanticscholar   +1 more source

Reorganization, specialization, and degradation of oocyte maternal components for early development

open access: yesReproductive Medicine and Biology, 2023
Background Oocyte components are maternally provided, solely determine oocyte quality, and coordinately determine embryo quality with zygotic gene expression.
Yuhkoh Satouh, Ken Sato
doaj   +1 more source

The RNA m6A Reader YTHDF2 Is Essential for the Post-transcriptional Regulation of the Maternal Transcriptome and Oocyte Competence

open access: yesMolecules and Cells, 2017
Summary YTHDF2 binds and destabilizes N6-methyladenosine (m6A)-modified mRNA. The extent to which this branch of m6A RNA-regulatory pathway functions in vivo and contributes to mammalian development remains unknown. Here we find that YTHDF2 deficiency is
Ivayla Ivanova   +9 more
semanticscholar   +1 more source

GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. [PDF]

open access: yesPLoS Genetics, 2017
Folliculogenesis is a progressive and highly regulated process, which is essential to provide ova for later reproductive life, requires the bidirectional communication between the oocyte and granulosa cells.
Chen Jiang   +12 more
doaj   +1 more source

THE EFFECTIVITY OF CYSTEAMINE SUPPLEMENTATION ON IMPROVING THE IN VITRO FERTILIZATION RATE OF SHEEP OOCYTES

open access: yesJurnal Kedokteran Hewan, 2021
The purpose of this study was to evaluate the effectiveness of cysteamine supplementation on the maturation medium and/or in vitro fertilization medium with regards to improving the normal fertilization rate of sheep oocytes, which are characterized by ...
Dona Astari Nurkarimah   +3 more
doaj   +1 more source

Aspects of follicular and oocyte maturation that affect the developmental potential of embryos.

open access: yesJournal of reproduction and fertility. Supplement, 2019
The ability to mature, be fertilized and finally to develop into a viable embryo is acquired gradually by the oocyte during progressive differentiation throughout folliculogenesis.
P. Mermillod, B. Oussaid, Y. Cognié
semanticscholar   +1 more source

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