GGPP-Mediated Protein Geranylgeranylation in Oocyte Is Essential for the Establishment of Oocyte-Granulosa Cell Communication and Primary-Secondary Follicle Transition in Mouse Ovary. [PDF]
Folliculogenesis is a progressive and highly regulated process, which is essential to provide ova for later reproductive life, requires the bidirectional communication between the oocyte and granulosa cells.
Chen Jiang+12 more
doaj +1 more source
Inferring simple but precise quantitative models of human oocyte and early embryo development [PDF]
Macroscopic, phenomenological models have proven useful as concise framings of our understandings in fields from statistical physics to economics to biology. Constructing a phenomenological model for development would provide a framework for understanding the complicated, regulatory nature of oogenesis and embryogenesis.
arxiv
The fertilizing spermatozoon is a highly specialized cell that selects from millions along the female tract until the oocyte. The paternal components influence the oocyte activation during fertilization and are fundamental for normal embryo development ...
Mohammad Ishraq Zafar+2 more
doaj +1 more source
The art of oocyte meiotic arrest regulation
A central dogma of mammalian reproductive biology is that the size of the primordial follicle pool represents reproductive capacity in females. The assembly of the primordial follicle starts after the primordial germ cells (PGCs)-derived oocyte releases ...
Bo Pan, Julang Li
semanticscholar +1 more source
Aims:The aim of this study is to evaluate and compare multiple obstetric and perinatal outcomes between donor-oocyte in vitro fertilization (IVF) and self-oocyte IVF group. Settings and Design: This study was done in a tertiary care center with ART unit.
Vikas Yadav+5 more
doaj +1 more source
Active mechanics reveal molecular-scale force kinetics in living oocytes [PDF]
Active diffusion of intracellular components is emerging as an important process in cell biology. This process is mediated by complex assemblies of molecular motors and cytoskeletal filaments that drive force generation in the cytoplasm and facilitate enhanced motion. The kinetics of molecular motors have been precisely characterized in-vitro by single
arxiv +1 more source
The epidermal growth factor network: role in oocyte growth, maturation and developmental competence
BACKGROUND The LH surge induces great physiological changes within the preovulatory follicle, which culminate in the ovulation of a mature oocyte that is capable of supporting embryo and foetal development.
D. Richani, R. Gilchrist
semanticscholar +1 more source
Glycolytic metabolites are critical modulators of oocyte maturation and viability. [PDF]
The maturation of an oocyte into an egg is a key step in preparation for fertilization. In Xenopus, oocyte maturation is independent of transcription, being regulated at the level of translation and post-translational modifications of proteins.
Lloyd Berger, Andrew Wilde
doaj +1 more source
Cortical microtubule nucleation can organise the cytoskeleton of $Drosophila$ oocytes to define the anteroposterior axis [PDF]
Many cells contain non-centrosomal arrays of microtubules (MT), but the assembly, organisation and function of these arrays are poorly understood. We present the first theoretical model for the non-centrosomal MT cytoskeleton in $Drosophila$ oocytes, in which $bicoid$ and $oskar$ mRNAs become localised to establish the anterior-posterior body axis ...
arxiv +1 more source
Oocyte specific lncRNA variant Rose influences oocyte and embryo development
Fully grown mammalian oocytes store a large amount of RNA synthesized during the transcriptionally active growth stage. A large part of the stored RNA belongs to the long non-coding class which contain either transcriptional noise or important ...
Rajan Iyyappan+5 more
doaj