Results 41 to 50 of about 241,792 (308)

Transcriptome Landscape of Human Folliculogenesis Reveals Oocyte and Granulosa Cell Interactions.

Molecules and Cells, 2018
The dynamic transcriptional regulation and interactions of human germlines and surrounding somatic cells during folliculogenesis remain unknown. Using RNA sequencing (RNA-seq) analysis of human oocytes and corresponding granulosa cells (GCs) spanning ...
Yaoyao Zhang, Zhiqiang Yan, Qingyuan Qin, V. Nisenblat, Hsun‐Ming Chang, Yang Yu, Tianren Wang, Cui-ling Lu, Ming Yang, Shuo Yang, Ying Yao, Xiaohui Zhu, Xi Xia, Yujiao Dang, Yixin Ren, Peng Yuan, Rong Li, Ping Liu, Hongyan Guo, Jinsong Han, Haojie He, Kun Zhang, Yiting Wang, Yu Wu, Meng Li, J. Qiao, Jie Yan, Liying Yan   +27 more
semanticscholar   +1 more source

Effect of Endometriosis on Cumulus ATP, Number of Mitochondria and Oocyte Maturity in Cumulus Oocyte Complex in Mice

Revista Brasileira de Ginecologia e Obstetrícia, 2023
Objective Endometriosis causes a decrease in oocyte quality. However, this mechanism is not fully understood. The present study aimed to analyze the effect of endometriosis on cumulus cell adenosine triphosphate ATP level, the number of mitochondria, and
Muhammad Ardianta Widyanugraha, Widjiati Widjiati, Hendy Hendarto   +2 more
doaj   +1 more source

The art of oocyte meiotic arrest regulation

Reproductive Biology and Endocrinology, 2019
A central dogma of mammalian reproductive biology is that the size of the primordial follicle pool represents reproductive capacity in females. The assembly of the primordial follicle starts after the primordial germ cells (PGCs)-derived oocyte releases ...
Bo Pan, Julang Li
semanticscholar   +1 more source

A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development

Cell Reports
Summary: Embryonic genome activation (EGA) marks the transition from dependence on maternal transcripts to an embryonic transcriptional program. The precise temporal regulation of gene expression, specifically the silencing of the Dux/murine endogenous ...
Yunan Ye, Hayden Anthony Homer
doaj   +1 more source

Comparison of obstetric outcomes of pregnancies after donor-oocyte In vitro fertilization and self-oocyte In vitro fertilization: A retrospective cohort study

Journal of Human Reproductive Sciences, 2018
Aims:The aim of this study is to evaluate and compare multiple obstetric and perinatal outcomes between donor-oocyte in vitro fertilization (IVF) and self-oocyte IVF group. Settings and Design: This study was done in a tertiary care center with ART unit.
Vikas Yadav, Priyanka Bakolia, Neena Malhotra, Reeta Mahey, Neeta Singh, Alka Kriplani   +5 more
doaj   +1 more source

Glycolytic metabolites are critical modulators of oocyte maturation and viability. [PDF]

PLoS ONE, 2013
The maturation of an oocyte into an egg is a key step in preparation for fertilization. In Xenopus, oocyte maturation is independent of transcription, being regulated at the level of translation and post-translational modifications of proteins.
Lloyd Berger, Andrew Wilde
doaj   +1 more source

Lipid modification to improve cryotolerance of gametes, embryos and larvae and its potential application in aquaculture species: a review

Frontiers in Marine Science, 2023
Cryopreservation is a technique to maintain biological materials’ physiological and genetic stability at an ultralow temperature. For commercially important livestock or aquatic species, gamete and embryo cryopreservation could play a significant role in
Xiaochen Zhu, Xiaochen Zhu, Penny Miller-Ezzy, Yingying Zhao, Jianguang Qin, Youhong Tang, Yibing Liu, Xiaoxu Li, Xiaoxu Li   +8 more
doaj   +1 more source

Oocyte-secreted factors enhance oocyte developmental competence

Developmental Biology, 2006
The capacity of fully grown oocytes to regulate their own microenvironment by paracrine factors secreted by the oocyte (oocyte-secreted factors, OSFs) may in turn contribute to oocyte developmental competence. Here, we investigated if OSFs have a direct influence on oocyte developmental competence during in vitro maturation (IVM). Bovine cumulus-oocyte
Hussein, T., Thompson, J., Gilchrist, R.
openaire   +3 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source