Results 41 to 50 of about 265,248 (262)
Scientific Reports, 2017 An increase in intraovarian reactive oxygen species (ROS) has long been implicated in the decline in oocyte quality associated with maternal ageing. Oxidative stress (OS)-induced lipid peroxidation and the consequent generation of highly electrophilic ...
Bettina P Mihalas +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li +22 more
wiley +1 more source
Soft Micromanipulation Robot for Real‐Time Adaptive Multimodal Operation
Advanced Science, EarlyView.This manuscript proposes a soft micromanipulator robot (SMR) for “full‐angle” precision biomedical operations. Bio‐inspired SMR achieves omnidirectional motion, micrometer precision, and multimodal capabilities including aspiration, transfer, rotation, assembly, injection, and cutting.
Zhuowei Li +8 more
wiley +1 more source
Human Reproduction, 2016 Study question Can a counseling tool be developed for women desiring elective oocyte cryopreservation to predict the likelihood of live birth based on age and number of oocytes frozen? Summary answer Using data from ICSI cycles of a population of women
R. Goldman +5 more
semanticscholar +1 more source
Pushing Biomolecule Detection Limit With Graphene Field‐effect Transistor Biosensors
Advanced Electronic Materials, EarlyView.Graphene knows your health! This work presents a comprehensive overview of recent advances in graphene field‐effect transistor (GFET) biosensors for ultrasensitive biomolecule detection. How device engineering, high‐mobility graphene synthesis, and tailored surface chemistry push detection limits is highlighted, while discussing emerging strategies ...
Co Dang Pham +4 more
wiley +1 more source
P-209 Implication of delta opioid receptor in the in vitro maturation of oocytes and its effects on subsequent fertilization and embryo development in mice [PDF]
, 2023 Lide Totorikaguena +2 more
openalex +1 more source
Animal Models and Experimental Medicine, EarlyView.Brefeldin A (BFA) significantly inhibits oocyte release and induces apoptosis in ovarian granulosa cells by disrupting follicular development. It downregulates proliferation‐associated genes, reduces SIRT1/SIRT6 proteins, and upregulates cell cycle inhibitors P21 and P16. Additionally, BFA impairs estrogen synthesis and affects ovarian function through
Yao Jiang +8 more
wiley +1 more source
The Role of Oocyte Organelles in Determining Developmental Competence
Biology, 2017 The ability of an oocyte to undergo successful cytoplasmic and nuclear maturation, fertilization and embryo development is referred to as the oocyte’s quality or developmental competence.
K. Reader +2 more
semanticscholar +1 more source
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
Animal Models and Experimental Medicine, EarlyView.We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source
Reproductive Medicine and Biology, 2016 Reactive oxygen species (ROS) are required for cellular functioning and are controlled by anti‐oxidants. The ROS influence the follicles, oocytes, endometrium, and their environment.
Manika Kala +2 more
semanticscholar +1 more source