Results 51 to 60 of about 265,248 (262)
Animal Research and One Health, EarlyView.The paper is divided into three main sections: a review of the development of spatial transcriptomics technology, its applications in livestock and poultry research, and its future prospects. This article provides an overview of the current state of spatial transcriptomics in animal research, exploring its integration with multiomics technologies as ...
Mingyu Wang +5 more
wiley +1 more source
Essential Role of Granulosa Cell Glucose and Lipid Metabolism on Oocytes and the Potential Metabolic Imbalance in Polycystic Ovary Syndrome [PDF]
, 2023 Chen-Hua Zhang, Xiangyi Liu, Jing Wang
openalex +1 more source
Aging, 2017 Oxidative stress is known as a major contributing factor involved in oocyte aging, which negatively affects oocyte quality and development after fertilization. Melatonin is an effective free radical scavenger and its metabolites AFMK and AMK are powerful
Tao Wang +8 more
semanticscholar +1 more source
Animal Research and One Health, EarlyView.Conserving genetic material and even increasing genetic diversity is critical. To conduct the conservation of wild boar germplasm resources, we have successfully obtained healthy cloned wild boars for the first time using interspecies somatic cell nuclear transfer and established transgene‐free iPSCs that can be used to conduct iterative rounds of gene
Chen Gao +11 more
wiley +1 more source
NLRP14 Safeguards Calcium Homeostasis via Regulating the K27 Ubiquitination of Nclx in Oocyte‐to‐Embryo Transition [PDF]
, 2023 Tie‐Gang Meng +22 more
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Both diet and gene mutation induced obesity affect oocyte quality in mice
Scientific Reports, 2016 Obesity was shown to cause reproductive dysfunctions such as reduced conception, infertility and early pregnancy loss. However, the possible effects of obesity on oocyte quality are still not fully understood. In this study we investigated the effects of
Yan-jun Hou +5 more
semanticscholar +1 more source
BMEMat, EarlyView.This perspective positions Stereo‐cell as a scalable, unbiased capture platform that unifies phenotypes, spatial context, transcriptomics, proteomics, and EV detection on‐chip. By integrating imaging and CITE‐style readouts with subcellular spatial transcriptomics, it resolves rare and large cells alike. We highlight applications from PBMC benchmarking
Chao Wang +7 more
wiley +1 more source
Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage
Chemistry &Biodiversity, EarlyView.Graphical abstract of Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage ABSTRACT Antineoplastic agents can induce tissue damage through oxidative stress mechanisms. Doxorubicin, a widely used chemotherapeutic agent, has been shown to cause permanent damage to reproductive tissues.
Meltem Arıkan Malkoc +3 more
wiley +1 more source
Oocyte cryopreservation for age-related fertility loss [PDF]
, 2012 Wybo Dondorp +7 more
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PLK4: Master Regulator of Centriole Duplication and Its Therapeutic Potential
Cytoskeleton, EarlyView.ABSTRACT Centrosomes catalyze the assembly of a microtubule‐based bipolar spindle, essential for the precise chromosome segregation during cell division. At the center of this process lies Polo‐Like Kinase 4 (PLK4), the master regulator that controls the duplication of the centriolar core to ensure the correct balance of two centrosomes per dividing ...
Muhammad Hamzah +2 more
wiley +1 more source