Fertility preservation in gynaecologic cancers [PDF]
Due to substantial improvement in the diagnosis and treatment of gynaecologic cancers, a better understanding of patient care needs to be revised. We reviewed the literature related to fertility preservation strategies in gynaecological cancer and ...
De Felice, Francesca +9 more
core +1 more source
Probing lasting cryoinjuries to oocyte-embryo transcriptome.
Clinical applications of oocytes cryopreservation include preservation of future fertility of young cancer patients, substitution of embryo freezing to avoid associated legal and ethical issues, and delaying childbearing years.
Binnur Eroglu +4 more
doaj +1 more source
Mechanisms of chemotherapy-induced human ovarian aging: double strand DNA breaks and microvascular compromise [PDF]
The mechanism of chemotherapy-induced acceleration of ovarian aging is not fully understood. We used doxorubicin, a widely used cancer chemotherapeutic, in a variety of in vivo xenograft, and in vitro models to investigate the impact of chemotherapy ...
Darzynkiewicz, Zbigniew +3 more
core +1 more source
Fertility treatment outcomes in transgender men with a history of testosterone therapy
Objective: To evaluate fertility treatment outcomes among transgender (TG) men with a history of gender-affirming hormone therapy with exogenous testosterone. Design: Descriptive, retrospective cohort study.
Atoosa Ghofranian, M.D. +6 more
doaj +1 more source
Fertilization capacity with rainbow trout DNA-damaged sperm and embryo developmental success [PDF]
Mammalian spermatozoa undergo a strong selection process along the female tract to guarantee fertilization by good quality cells, but risks of fertilization with DNA-damaged spermatozoa have been reported.
Ahmadi +31 more
core +1 more source
Mammalian Oocyte Cryopreservation - Review
Although oocyte cryopreservation represents one of the main objectives of the reproductive medicine and cryobiology in the last years, until now, regardless of the studied specie, there is no freezing protocol that will assure satisfactory survival rates
Ada Cean +4 more
doaj
Female Fertility: Is it Safe to "Freeze?"
Objective: To evaluate the safety and risk of cryopreservation in female fertility preservation. Data sources: The data analyzed in this review were the English articles from 1980 to 2013 from journal databases, primarily PubMed and Google scholar. The
Lu Zhang +4 more
doaj +1 more source
Enhancement of neoangiogenesis and follicle survival by sphingosine-1-phosphate in human ovarian tissue xenotransplants [PDF]
Ovarian transplantation is one of the key approaches to restoring fertility in women who became menopausal as a result of cancer treatments. A major limitation of human ovarian transplants is massive follicular loss during revascularization.
Soleimani, Reza +2 more
core +3 more sources
Implications of storage and handling conditions on glass transition and potential devitrification of oocytes and embryos [PDF]
Devitrification, the process of crystallization of a formerly crystal-free, amorphous glass state, can lead to damage during the warming of cells.
Sansinena, Marina Julia +3 more
core +1 more source
Fine morphological assessment of quality of human mature oocytes after slow freezing or vitrification with a closed device: a comparative analysis [PDF]
BACKGROUND: Human mature oocytes are very susceptible to cryodamage. Several reports demonstrated that vitrification might preserve oocyte better than slow freezing. However, this is still controversial.
A. Borini +7 more
core +2 more sources

