Results 141 to 150 of about 6,215 (307)

Cathepsin B Regulates Ovarian Reserve Quality and Quantity via Mitophagy by Modulating IGF1R Turnover

open access: yesAging Cell, EarlyView.
Autophagy regulates ovarian reserve, with Cathepsin B playing a critical role in aging. Inhibition of Cathepsin B increases follicle count, enhances IGF1R–AKT–mTOR signaling and improves mitochondrial function without compromising fertility. This conserved mechanism suggests potential therapeutic strategies to delay ovarian aging and sustain fertility,
Aradhana Mohanty   +8 more
wiley   +1 more source

Successful triplet pregnancy in a 51-year-old woman after oocyte donation

open access: green, 1997
Randolph V. Neal   +3 more
openalex   +2 more sources

The oocytes donation as a model to study the effect of estradiol level on oocytes quality. [PDF]

open access: bronze, 2001
Fidel Cano   +5 more
openalex   +1 more source

Mitochondrial Respiratory Dysfunction Is Not Correlated With Mitochondrial Genotype in Premature Aging Mice

open access: yesAging Cell, EarlyView.
The causal relationship between random mtDNA mutations and reduced mitochondrial respiratory activity in premature aging Polgmut/mut mice remains unclear. This study shows that the abnormal mitochondrial function in Polgmut/mut mice is more closely associated with the nuclear Polg genotype than with the mtDNA genotype.
Hiroaki Tamashiro   +4 more
wiley   +1 more source

Elective Oocyte Cryopreservation [PDF]

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd
Introduction: In recent years, techniques for oocyte cryopreservation have aided in preserving women's fertility. Initially, oocyte cryopreservation was implemented for females with diminished ovarian reserves.
Saeideh Dashti, Maryam Eftekhar
doaj  

Oocyte sharing donation

open access: bronze, 1997
J.F.T. Jucá M.O.H. Mariano R.L. Lopes   +9 more
openalex   +1 more source

Use of midcycle GnRH antagonist for patients awaiting oocyte donation due to poor ovarian response and multiple trials of IVF. [PDF]

open access: bronze, 2001
V.C Giraldo   +5 more
openalex   +1 more source

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

open access: yesAging Cell, EarlyView.
Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin‐free medium. Single nuclei sequencing and proteomics revealed an unbiased signature of ovarian senescence driven by epithelial cells in the cortex and stromal cells in the cortex and medulla ...
Pooja Raj Devrukhkar   +18 more
wiley   +1 more source

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