Results 241 to 250 of about 167,796 (316)

Testicular SIRT1 Loss Reveals an Aging‐Like Proteomic Landscape and Precipitates Reproductive Deterioration

Andrology, EarlyView.
ABSTRACT Background Advanced paternal age is associated with reduced male fertility and testicular dysfunction. Among the molecular regulators involved in aging, SIRT1, a NAD+‐dependent deacetylase, plays a pivotal role in maintaining oxidative balance and cellular homeostasis.
María Iniesta‐Cuerda, Jiřina Havránková, Hedvika Řimnáčová, Jiří Moravec, František Liška, Martin Knytl, Milena Králíčková, Jan Nevoral   +7 more
wiley   +1 more source

Age-related upregulation of p16 expression in mouse ovarian somatic cells correlated with reproductive function decline p16 expression and ovarian aging in mice. [PDF]

PLoS One
Sato Y, Kawagoe Y, Kawamura K.
europepmc   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Psychological depression and its association with oocyte yield and embryo outcomes in infertile women undergoing <i>in vitro</i> fertilization-embryo transfer. [PDF]

Front Psychiatry
Song XH, Yin YT, Jia YD, Wang JY, Wang H, Wang DN.   +5 more
europepmc   +1 more source

Improvement of Mouse Spermatozoa Freezing at ‐80°C With Ascorbic Acid 2‐Glucoside at Thawing Phase

Andrology, EarlyView.
ABSTRACT Background Sperm cryopreservation is the most common method to maintain a great number of mutant mouse lines. However, the use of liquid nitrogen (LN2) for freezing presents considerable problems in terms of cost, safety, and accessibility. For this reason, the storage of semen samples at ‐80° in ultra‐freezers has been increasingly used in ...
Alessia Paradiso, Renata Paoletti, Simone Cassetti, Nicola Bernabò, Barbara Barboni, Marcello Raspa, Ferdinando Scavizzi   +6 more
wiley   +1 more source

Guinea pig δβγ-ENaC is locked in an open state and uncoupled from regulation by proteases. [PDF]

Pflugers Arch
Lawong RY, Etang EC, May F, Vorrat P, Rauh O, Althaus M.   +5 more
europepmc   +1 more source

Hyperactivation and Tyrosine Phosphorylation of Cryopreserved Stallion Spermatozoa in Relation to Conventional In Vitro Fertilization Blastocyst Production

Andrology, EarlyView.
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro, Carolina C. Porflidt, Alexandra L. Ash, Jacobo S. Rodriguez, Perla D. Fleury, Edward L. Squires, Elaine M. Carnevale   +6 more
wiley   +1 more source

Transcriptomic Analysis of Bovine Oocytes at GV and MII Stages and Dynamic Changes in Key Gene Expression Patterns. [PDF]

Biology (Basel)
Wang X, Huang F, Li X, Hu K, Chen H, Niu P, Qu H, Fang D, Han C, Gao Q.   +9 more
europepmc   +1 more source

In Vitro Sperm–Epididymosomes Interaction Immediately Before Fertilization Changes Sperm Fertility Potential

Andrology, EarlyView.
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves, Maria Alice de Almeida, Ana Beatriz Bossois Moura, Laura Gabrielli Haupenthal, Raissa Braido Rangel, Flávio Vieira Meirelles, Juliano Coelho da Silveira, Felipe Perecin   +7 more
wiley   +1 more source