Results 271 to 280 of about 280,910 (369)

Oxygen Consumption of Maturing Rat Oocytes [PDF]

open access: bronze, 1977
Claes Magnusson   +4 more
openalex   +1 more source

Cathepsin B Regulates Ovarian Reserve Quality and Quantity via Mitophagy by Modulating IGF1R Turnover

open access: yesAging Cell, EarlyView.
Autophagy regulates ovarian reserve, with Cathepsin B playing a critical role in aging. Inhibition of Cathepsin B increases follicle count, enhances IGF1R–AKT–mTOR signaling and improves mitochondrial function without compromising fertility. This conserved mechanism suggests potential therapeutic strategies to delay ovarian aging and sustain fertility,
Aradhana Mohanty   +8 more
wiley   +1 more source

Equivalent outcomes of human oocytes after vitrification or slow freezing with a modified rehydration protocol. [PDF]

open access: yesReprod Biol Endocrinol
Papis K   +5 more
europepmc   +1 more source

Mitochondrial Respiratory Dysfunction Is Not Correlated With Mitochondrial Genotype in Premature Aging Mice

open access: yesAging Cell, EarlyView.
The causal relationship between random mtDNA mutations and reduced mitochondrial respiratory activity in premature aging Polgmut/mut mice remains unclear. This study shows that the abnormal mitochondrial function in Polgmut/mut mice is more closely associated with the nuclear Polg genotype than with the mtDNA genotype.
Hiroaki Tamashiro   +4 more
wiley   +1 more source

Impact of Curcumin on Frozen Bovine Sperm Quality and In Vitro Bovine Oocyte Maturation. [PDF]

open access: yesVet Sci
Lin H   +10 more
europepmc   +1 more source

A Comprehensive Multiomics Signature of Doxorubicin‐Induced Cellular Senescence in the Postmenopausal Human Ovary

open access: yesAging Cell, EarlyView.
Explants of human postmenopausal ovarian cortex and medulla were treated with doxorubicin for 24 h followed by culture for up to 10 days in doxorubicin‐free medium. Single nuclei sequencing and proteomics revealed an unbiased signature of ovarian senescence driven by epithelial cells in the cortex and stromal cells in the cortex and medulla ...
Pooja Raj Devrukhkar   +18 more
wiley   +1 more source

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