Oogenesis: Matrix Revolutions [PDF]
The mechanism of egg-chamber elongation during Drosophila oogenesis has always been mysterious. A new study shows that the egg chambers spin around their long axis laying down polarised extracellular matrix, which acts as a molecular corset to restrict radial expansion.
Bastock, Rebecca, St Johnston, Daniel
openaire +2 more sources
Localisation of RNAs into the germ plasm of vitellogenic xenopus oocytes [PDF]
We have studied the localisation of mRNAs in full-grown Xenopus laevis oocytes by injecting fluorescent RNAs, followed by confocal microscopy of the oocyte cortex.
B Heinrich +66 more
core +5 more sources
Genomic function during the lampbrush chromosome stage of amphibian oogenesis [PDF]
Throughout its lengthy developmental history the disposition of the genetic material in the amphibian oocyte nucleus differs from that in other cell types.
Crippa, Marco +3 more
core +1 more source
Effector Caspase Dcp-1 and IAP Protein Bruce Regulate Starvation-Induced Autophagy during Drosophila Melanogaster Oogenesis [PDF]
A complex relationship exists between autophagy and apoptosis, but the regulatory mechanisms underlying their interactions are largely unknown. We conducted a systematic study of Drosophila melanogaster cell death–related genes to determine their ...
Barbosa, Sharon González +4 more
core +4 more sources
Germ cell-intrinsic effects of sex chromosomes on early oocyte differentiation in mice.
A set of sex chromosomes is required for gametogenesis in both males and females, as represented by sex chromosome disorders causing agametic phenotypes. Although studies using model animals have investigated the functional requirement of sex chromosomes,
Norio Hamada +7 more
doaj +1 more source
Sequential Regulation of Maternal mRNAs through a Conserved cis-Acting Element in Their 3′ UTRs
Summary: Maternal mRNAs synthesized during oogenesis initiate the development of future generations. Some maternal mRNAs are either somatic or germline determinants and must be translationally repressed until embryogenesis.
Pooja Flora +9 more
doaj +1 more source
Non-Canonical, Somatic-Dependent Vertical Transmission of Wolbachia in an Aphid. [PDF]
We discovered a novel somatic‐associated Wolbachia transmission strategy in cedar bark aphids (Cinara cedri), contrasting with its typical maternal vertical transmission. This unique maternally retained somatic re‐acquisition strategy—a “piggybacking” on the highly efficient obligate symbiont transmission pathway—reveals diverse endosymbiont strategies
Nozaki T, Kobayashi Y, Shigenobu S.
europepmc +2 more sources
Ablation of the MiR-17-92 MicroRNA Cluster in Germ Cells Causes Subfertility in Female Mice
Background/Aims: Oogenesis is a highly complex process that is intricately regulated by interactions of multiple genes and signaling molecules. However, the underlying molecular mechanisms are poorly understood.
Jian Wang +4 more
doaj +1 more source
High-dose irradiation induces cell cycle arrest, apoptosis, and developmental defects during Drosophila oogenesis. [PDF]
Ionizing radiation (IR) treatment induces a DNA damage response, including cell cycle arrest, DNA repair, and apoptosis in metazoan somatic cells. Because little has been reported in germline cells, we performed a temporal analysis of the DNA damage ...
Hee Jin Shim +4 more
doaj +1 more source
Oogenesis is a highly orchestrated process that depends on regulation by autocrine/paracrine hormones and growth factors. However, many details of the molecular mechanisms that regulate fish oogenesis remain elusive.
Xiang Liu +26 more
doaj +1 more source

