Results 291 to 300 of about 16,336,802 (316)

Choice over placebo administration enhances open-label placebo hypoalgesia.

Pain, 2023
Many studies indicate that deceptively administered placebos can improve pain outcomes. However, the deception involved presents an ethical barrier to translation because it violates informed consent and patient autonomy.
Biya Tang, E. Livesey, Ben Colagiuri
semanticscholar   +3 more sources

Open-Label Placebo: Reflections on a Research Agenda

Perspectives in Biology and Medicine, 2018
Open-label placebos (OLP)-placebo pills honestly prescribed-have challenged the notion that placebos require either deception or concealment to evoke salubrious benefits. This essay describes how the author arrived at the counter-intuitive OLP hypothesis, discusses evidence for OLP effectiveness, and examines mechanistic explanations for OLP.
T. Kaptchuk
semanticscholar   +3 more sources

No acute effects of placebo or open-label placebo treatments on strength, voluntary activation, and neuromuscular fatigue

European Journal of Applied Physiology, 2019
Recent evidence suggests that deception may not be necessary for placebos to improve clinical outcomes. We tested the hypothesis that placebo and open-label placebo (OLP) treatments would acutely improve strength and voluntary activation, as well as minimize neuromuscular fatigue, in untrained participants.Twenty-one males (n = 11) and females (n = 10)
Jeffrey Stout, Rob Maclennan, David Fukuda   +2 more
exaly   +3 more sources

Is the rationale more important than deception? A randomized controlled trial of open-label placebo analgesia

Pain, 2017
Research on open-label placebos questions whether deception is a necessary characteristic of placebo effects. Yet, comparisons between open-label and deceptive placebos (DPs) are lacking.
C. Locher, Antje Frey Nascimento, I. Kirsch, Joe Kossowsky, A. Meyer, J. Gaab   +5 more
semanticscholar   +2 more sources

Open-label placebo reduces fatigue in cancer survivors: a randomized trial

Supportive Care in Cancer, 2018
Alexis Michaud, Ann Partridge, Eric Zhou   +2 more
exaly   +2 more sources

Open-Label-Placebo bei PMS-Beschwerden

gynäkologie + geburtshilfe
Katalin Wagner
semanticscholar   +2 more sources

Effects of open-label placebo on pain, functional disability and spine mobility in chronic back pain patients: a randomized controlled trial.

Pain, 2019
Chronic back pain is a major global health problem, while its treatment is hampered by a lack of efficacy and restricted safety profile of common front-line therapies.
J. Kleine-Borgmann, K. Schmidt, Andreas Hellmann, U. Bingel   +3 more
semanticscholar   +1 more source

Open-label placebo for chronic low back pain: a 5-year follow-up.

Pain, 2020
Long-term follow-up of patients treated with open-label placebo (OLP) are non-existent. Herein, we report a 5-year follow-up of a three-weeks OLP randomized controlled trial (RCT) in chronic low back pain patients.
Cláudia Carvalho, Mariana Pais, Lidia Cunha, Paula Rebouta, T. Kaptchuk, I. Kirsch   +5 more
semanticscholar   +1 more source

Remotely Provided Open-Label Placebo Reduces Frequency of and Impairment by Allergic Symptoms

Psychosomatic Medicine, 2021
Objective Placebos being prescribed with full honesty and disclosure (i.e., open-label placebo [OLP]) have been shown to reduce symptom burden in a variety of conditions.
Tobias Kube, I. Kirsch, J. Glombiewski, M. Witthöft, Anne-Kathrin Bräscher   +4 more
semanticscholar   +1 more source

Deceptive but not open label placebos attenuate motion-induced nausea

Journal of Psychosomatic Research, 2019
Nausea is a common complaint, known to respond to the placebo effect. Existing research has employed deception when administering placebos for nausea, limiting therapeutic translation on ethical grounds. We therefore examined the potential of non-deceptive open-label placebos (OLPs) to reduce nausea.Galvanic Vestibular Stimulation (GVS) and Virtual ...
K, Barnes, A, Yu, J, Josupeit, B, Colagiuri   +3 more
openaire   +2 more sources