Results 41 to 50 of about 156,514 (326)

Noble Humbug? Hard and soft laws on clinical placebo use [PDF]

Frontiers in Psychology
Despite the widespread historical and contemporary use of placebos in medicine, legal regulations addressing their administration remain limited in many countries.
Mélina Richard, Mélina Richard, Manuela Ganz, Lena Dominique Hornstein, Bohdan Stehlik, Mélanie Levy, Charlotte R. Blease, Marco Annoni, Bernice S. Elger, Jens Gaab   +9 more
doaj   +2 more sources

The role of patient beliefs in open-label placebo effects.

Health Psychology, 2019
OBJECTIVE Recent research on open-label placebos, or placebos administered without deception or concealment, suggests that they can be effective in a variety of conditions.
Kari A Leibowitz, E. Hardebeck, J. Goyer, Alia J. Crum   +3 more
semanticscholar   +4 more sources

Effects of open-label placebos across populations and outcomes: an updated systematic review and meta-analysis of randomized controlled trials [PDF]

Scientific Reports
This work synthesizes and updates findings from previous systematic-reviews and meta-analyses on open-label placebos (OLPs). For the first time, it directly tests whether OLPs differ in effects between clinical and non-clinical samples, and between self ...
Johannes C. Fendel, Carl Tiersch, Paul Sölder, Jens Gaab, Stefan Schmidt   +4 more
doaj   +2 more sources

Talking placebo: a qualitative study of patients’ attitudes toward open-label placebo implementation into clinical practice [PDF]

Frontiers in Psychology
BackgroundFor more than a decade, studies have supported the efficacy and safety of placebos without deception—so-called open-label placebos (OLPs)—to harness placebo effects in primary care while aligning with key ethical principles.
Antje Frey Nascimento, Berfin Bakis, Jens Gaab, Tobias Schneider, Athina Papadopoulou, Athina Papadopoulou, Milena Ritter, Michael H. Bernstein, Michael H. Bernstein, Charlotte R. Blease, Charlotte R. Blease, Cosima Locher, Cosima Locher   +12 more
doaj   +2 more sources

A systematic qualitative review of ethical issues in open label placebo in published research [PDF]

Scientific Reports
Open-label placebos (OLPs), which are transparently administered inert treatments, have gained increasing attention in the research community. They have the potential to harness placebo effects without deceiving the patient. The purpose of this study was
Mélina Richard, Michael Bernstein, Jens Gaab, Bernice Elger   +3 more
doaj   +2 more sources

Open-Label Placebo Injection for Chronic Back Pain With Functional Neuroimaging: A Randomized Clinical Trial.

JAMA Netw Open
Key Points Question What are the clinical effects and brain mechanisms of open-label (honestly prescribed) placebos for chronic back pain? Findings In this randomized clinical trial of 101 adults with chronic back pain, an open-label subcutaneous placebo
Ashar YK, Sun M, Knight K, Flood TF, Anderson Z, Kaptchuk TJ, Wager TD.   +6 more
europepmc   +2 more sources

Conditioned open-label placebos to facilitate opioid reduction in patients with chronic non-cancer pain: study protocol of a randomised controlled trial. [PDF]

BMJ Open
Carratta K, Bodonyi K, Frey Nascimento A, Friis D, von Känel R, Bircher L, Koechlin H, Bernstein M, Streitberger K, Arnet I, Roth AJ, Ronel J, Olliges E, Locher C.   +13 more
europepmc   +2 more sources

Author Correction: Effects of open-label placebos in clinical trials: a systematic review and meta-analysis [PDF]

Scientific Reports, 2021
Melina von Wernsdorff, Martin Loef, Brunna Tuschen‑Caffier, Stefan Schmidt   +3 more
doaj   +2 more sources

Open label placebo to treat fatigue in people with multiple sclerosis: feasibility and preliminary effects [PDF]

Pilot and Feasibility Studies
Background Fatigue is highly prevalent in adults with multiple sclerosis (MS) and current treatments offer limited benefit. It has been speculated that placebos only have an effect when they are administered with deception and concealment, which is ...
Navneet Kaur Baidwan, Tracy Tracy, Chia-Ying Chiu, Tanjila Nawshin, Teri Hoenemeyer, Emily Riser, Robert Motl, Kevin Fontaine, Tapan Mehta   +8 more
doaj   +2 more sources

Can Observational Learning Reinforce Open-label Placebo Hypoalgesia?

Pain, 2023
Previous research has indicated that an open-label placebo can reduce pain in both healthy participants and chronic pain patients. As nondeceptive placebos seem to be an effective and more ethical alternative to deceptive placebos, optimizing this kind of treatment is essential.
Justyna Brączyk, Przemysław Bąbel
openaire   +3 more sources