Introduction Several studies suggest that gut microbiota may play an important role in allergic diseases. The present trial aims to examine effects of the probiotic Enterococcus faecalis on symptoms of allergic rhinitis in patients.
Paul Enck, Michael Schaefer
doaj +2 more sources
Effects of open-label placebos across populations and outcomes: an updated systematic review and meta-analysis of randomized controlled trials [PDF]
This work synthesizes and updates findings from previous systematic-reviews and meta-analyses on open-label placebos (OLPs). For the first time, it directly tests whether OLPs differ in effects between clinical and non-clinical samples, and between self ...
Johannes C. Fendel +4 more
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Talking placebo: a qualitative study of patients’ attitudes toward open-label placebo implementation into clinical practice [PDF]
BackgroundFor more than a decade, studies have supported the efficacy and safety of placebos without deception—so-called open-label placebos (OLPs)—to harness placebo effects in primary care while aligning with key ethical principles.
Antje Frey Nascimento +12 more
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Public and professional attitudes towards deceptive and open-label placebo in functional neurological disorder and wider neurological practice [PDF]
Background Placebo effects are powerful and have been suggested to be particularly relevant in certain neurological conditions, including functional neurological disorder (FND).Methods A survey on attitudes towards and current practice of deceptive ...
Mark J Edwards +2 more
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Rethinking placebo: Exploring the effectiveness of
P. Bąbel
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A systematic qualitative review of ethical issues in open label placebo in published research [PDF]
Open-label placebos (OLPs), which are transparently administered inert treatments, have gained increasing attention in the research community. They have the potential to harness placebo effects without deceiving the patient. The purpose of this study was
Mélina Richard +3 more
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The role of patient beliefs in open-label placebo effects.
Recent research on open-label placebos, or placebos administered without deception or concealment, suggests that they can be effective in a variety of conditions. The current research sought to unpack the mechanisms underlying the treatment efficacy of open-label placebos.A health care provider induced an allergic reaction in 148 participants via a ...
Kari A. Leibowitz +3 more
openaire +4 more sources
Author Correction: Effects of open-label placebos in clinical trials: a systematic review and meta-analysis [PDF]
Melina von Wernsdorff +3 more
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Open label placebo to treat fatigue in people with multiple sclerosis: feasibility and preliminary effects [PDF]
Background Fatigue is highly prevalent in adults with multiple sclerosis (MS) and current treatments offer limited benefit. It has been speculated that placebos only have an effect when they are administered with deception and concealment, which is ...
Navneet Kaur Baidwan +8 more
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Open-label placebo for non-specific pain in the emergency department (OLP EM): study protocol for a mixed-method randomised control feasibility study in Switzerland. [PDF]
Degen B +5 more
europepmc +2 more sources

