Results 41 to 50 of about 8,591 (177)

Neural underpinnings of open-label placebo effects in emotional distress

Neuropsychopharmacology, 2022
AbstractWhile placebo effects are well-known, research in the last decade revealed intriguing effects that placebos may have beneficial effects even when given without deception. At first glance, this seems paradoxical, but several studies have reported improvements in pain, depression, or anxiety.
Michael Schaefer, Anja Kühnel, Felix Schweitzer, Sören Enge, Matti Gärtner   +4 more
openaire   +2 more sources

Informed consent and placebo effects: a content analysis of information leaflets to identify what clinical trial participants are told about placebos [PDF]

, 2012
BackgroundPlacebo groups are used in randomised clinical trials (RCTs) to control for placebo effects, which can be large. Participants in trials can misunderstand written information particularly regarding technical aspects of trial design such as ...
Adams, Alison E.M., Bishop, Felicity L., Kaptchuk, Ted J., Lewith, George   +3 more
core   +5 more sources

Placebos without deception: a randomized controlled trial in irritable bowel syndrome. [PDF]

PLoS ONE, 2010
Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception.
Ted J Kaptchuk, Elizabeth Friedlander, John M Kelley, M Norma Sanchez, Efi Kokkotou, Joyce P Singer, Magda Kowalczykowski, Franklin G Miller, Irving Kirsch, Anthony J Lembo   +9 more
doaj   +1 more source

Relieving pain using dose-extending placebos [PDF]

, 2016
Placebos are often used by clinicians, usually deceptively and with little rationale or evidence of benefit, making their use ethically problematic. In contrast with their typical current use, a provocative line of research suggests that placebos can be ...
Colloca, Luana, DeGrazia, David, Enck, Paul   +2 more
core   +1 more source

Efficacy of B-cell-targeted therapy with rituximab in patients with rheumatoid arthritis. [PDF]

, 2004
BACKGROUND: An open-label study indicated that selective depletion of B cells with the use of rituximab led to sustained clinical improvements for patients with rheumatoid arthritis. To confirm these observations, we conducted a randomized, double-blind,
Close, DR, Edwards, JCW, Emery, P, Filipowicz-Sosnowska, A, Shaw, T, Stevens, RM, Szczepanski, L, Szechinski, J   +7 more
core   +1 more source

Patients’ experiences treated with open-label placebo versus double-blind placebo: a mixed methods qualitative study [PDF]

BMC Psychology, 2022
Abstract Background There is increasing evidence suggesting that open-label placebo (OLP) is an effective treatment for several medical conditions defined by self-report. However, little is known about patients’ experiences with OLP, and no studies have directly compared patients’ experiences in double-blind placebo (DBP)
Haas, Julia W., Ongaro, Giulio, Jacobson, Eric, Conboy, Lisa A., Nee, Judy, Iturrino, Johanna, Rangan, Vikram, Lembo, Anthony, Kaptchuk, Ted J., Ballou, Sarah   +9 more
openaire   +5 more sources

Noninvasive vagus nerve stimulation as acute therapy for migraine. The randomized PRESTO study [PDF]

, 2018
Objective: To evaluate the efficacy, safety, and tolerability of noninvasive vagus nerve stimulation (nVNS; gammaCore; electroCore, LLC, Basking Ridge, NJ) for the acute treatment of migraine in a multicenter, double-blind, randomized, sham-controlled ...
Ambrosini, Anna, Barbanti, Piero, De Tommaso, Marina, Dorlas, Stefanie, Geppetti, Pierangelo, Grazzi, Licia, Liebler, Eric, Martelletti, Paolo, Negro, Andrea, Pierangeli, Giulia, Rainero, Innocenzo, Sarchielli, Paola, Tassorelli, Cristina   +12 more
core   +2 more sources

Psychological determinants of whole-body endurance performance [PDF]

, 2015
Background: No literature reviews have systematically identified and evaluated research on the psychological determinants of endurance performance, and sport psychology performance-enhancement guidelines for endurance sports are not founded on a ...
A Bandura, A Hatzigeorgiadis, A Kühberger, A Miller, A Renfree, AE Bauman, Alister McCormick, AW Blanchfield, B Donohue, B Donohue, B Pageaux, BD Franks, BH Thomas, BPC Smirmaul, BS Rushall, BW Brewer, C MacMahon, Carla Meijen, CD Stevinson, CI Karageorghis, CI Karageorghis, CJ Beedie, CRD Wagstaff, D Bath, DB Hollander, DE Saintsing, DT Campbell, E Lind, G Tenenbaum, G Tenenbaum, GL Martin, HS Hodgins, HS Jones, J Baker, J Barker, J Cohen, J Corbett, J Dosil, J Simons, J Stoeber, J Taylor, J Taylor, JA Jackson, JH Wilmore, JH Wilmore, JJ Martin, JL Andreacci, JL Kress, JW Brehm, KS Masters, LB Kyllo, LF Chitwood, LM Scott, M Bérdi, M Hojat, M Houston, M Hulleman, M Kellmann, M Miller, M Muraven, M Petticrew, M Sheard, M Viru, MJ Barwood, MJ Barwood, MP Buman, N Brick, NL Holt, P Lindsay, P Post, P Salmon, PB Gastin, PM Beeson, R Desharnais, R Weinberg, RA Hamilton, RA Wright, RC Thelwell, RC Thelwell, RJ Moffatt, RM Ryan, RS Burhans, RS Weinberg, S Marcora, S Marcora, S Michie, S Tuffey, Samuele Marcora, SB Morris, SJ Caird, SL Halson, SL Higgs, SM Marcora, SM Marcora, TD Noakes, TD Patrick, TE Scruggs, TM Okwumabua, VR Clark, W Borg, WJ Bubb, WJ Rejeski, WP Morgan, WP Morgan, WR Boot, WW Peveler, Y Theodorakis   +106 more
core   +4 more sources

The role of positive information provision in open‐label placebo effects

Applied Psychology: Health and Well-Being, 2023
Abstract Open label placebos (OLPs) appear generally efficacious among clinical samples, but the empirical evidence regarding their use in non‐clinical and sub‐clinical samples, as well as when administered independent of a convincing rationale, is mixed. Healthy participants ( N
Kirsten Barnes, Emily Babbage, Jessica Barker, Natasha Jain, Kate Faasse   +4 more
openaire   +2 more sources

Placebos in primary care? a nominal group study explicating UK GP and patient views of six theoretically plausible models of placebo practice

BMJ Open, 2020
ObjectivesTo better understand which theoretically plausible placebogenic techniques might be acceptable in UK primary care.DesignA qualitative study using nominal group technique and thematic analysis.
Adam W A Geraghty, Mohana Ratnapalan, Beverly Coghlan, Mengxin Tan, Hazel Everitt, George Lewith, Felicity L Bishop   +6 more
doaj   +1 more source