Results 51 to 60 of about 15,877,700 (238)
Placebos in the era of open‐label trials: An update for clinicians [PDF]
European Journal of Clinical Investigation, 2018 AbstractPlacebos have been used extensively by vast numbers of physicians, in a majority of clinical trials. Placebo effects involve behavioural, psychological and genetic factors and have been subject to ethical controversies stemming from the use of deception in treating patients.
Iftach Sagy +3 more
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Preferences for Anxiety Treatment with Open-Label Placebos
, 2021 Recently, researchers have begun to study the effects of open-label placebos (OLPs)—placebos administered to patients who are provided comprehensive information about placebos, including that the treatment is not active medication—to prevent unethical ...
Kelly Clemens +2 more
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, 2022 Nonmarital romantic breakups are difficult and emotionally painful experiences. Recovery can take from weeks to months, and there are very few established interventions that exist for helping to promote recovery.
Rice, Gabrielle
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Neural underpinnings of open-label placebo effects in emotional distress
Neuropsychopharmacology, 2022 AbstractWhile placebo effects are well-known, research in the last decade revealed intriguing effects that placebos may have beneficial effects even when given without deception. At first glance, this seems paradoxical, but several studies have reported improvements in pain, depression, or anxiety.
Michael Schaefer +4 more
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Effects of placebos without deception compared with no treatment: a systematic review and meta-analysis [PDF]
, 2017 Aim Our aim was to address the clinical efficacy of open-label placebos compared with no treatment by systematic review, and meta-analysis where possible.
Roberts, N. +7 more
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Placebos without deception: a randomized controlled trial in irritable bowel syndrome. [PDF]
PLoS ONE, 2010 Placebo treatment can significantly influence subjective symptoms. However, it is widely believed that response to placebo requires concealment or deception.
Ted J Kaptchuk +9 more
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The role of positive information provision in open‐label placebo effects
Applied Psychology: Health and Well-Being, 2023 Abstract Open label placebos (OLPs) appear generally efficacious among clinical samples, but the empirical evidence regarding their use in non‐clinical and sub‐clinical samples, as well as when administered independent of a convincing rationale, is mixed. Healthy participants ( N
Kirsten Barnes +4 more
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Can an Open-Label Placebo Be as Effective as a Deceptive Placebo? Methodological Considerations of a Study Protocol [PDF]
Medicines, 2020 Background: Placebo has been studied for many years and is ever-present in healthcare. In clinical practice, its use is limited by ethical issues raised by the deception entailed by its administration. Objective: To investigate whether, when given detailed information about pain and underlying placebo mechanisms, subjects will have a response similar ...
Leo Druart +6 more
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, 2023 Übergewicht und Adipositas im Kindesalter gehen mit einer Vielzahl chronischer Erkrankungen und einer erhöhten Mortalität bereits im jungen Erwachsenenalter einher.
Kujawa, Ben
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Why psychotherapy is an open-label placebo and open-label placebos are psychotherapy
, 2023 Abstract In recent years, placebos have undergone a rapid development from methodological chaff to therapeutic wheat. Hereby, the role of placebos as a deceptive control in clinical trials, as well as negative denomination for anything murky, changed to an innovative promise, an effective as well as ethical treatment.
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