Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FM Puzzle: Sick Building and Sydney`s Open-plan Offices
, 2001 FM Puzzle: Sick Building and Sydney`s Open-plan ...
G Treloar (13279797) +3 more
core
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
RNA‐related functions of BRCA2 in transcription, replication, and genome stability
FEBS Letters, EarlyView.Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda +2 more
wiley +1 more source
Building Bridges Across Archives. Open Jerusalem Workshop in Paris
, 2017 Building Bridges Across Archives. Designing Open Jerusalem Web Platform The second annual workshop of the ERC project Open Jerusalem will be held at Limonade&Co (Paris) and the French Foreign Office Archives (La Courneuve) on 9-10 May 2017. The workshop
Open Jerusalem
core +1 more source
DAYLIGHTING PERFORMANCE OF HORIZONTAL LIGHT PIPE BRANCHING ON OPEN PLAN OFFICE SPACE
Dimensi: Journal of Architecture and Built Environment, 2015 For daylighting purpose, office buildings should have a shallow plan and increase the ratio of surface to building’s volume. However, intensive use of air-conditioning drives office building’s plan to be deep with a minimum surface to volume ratio.
Feny ELSIANA +2 more
doaj
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
THE INVESTIGATION OF OPEN-PLAN OFFICE SOUND’S EFFECT ON STAFF’S COGNITIVE PERFORMANCE [PDF]
Salāmat-i kār-i ĪrānINTRODUCTION: Exposure to environmental sounds (noise pollution) is a key global public health concern that has implications for health and well-being (1).
Mohammad Ghashghaei +3 more
doaj
Open-plan office, employees’ enactment, interpretations and reactions to territoriality
, 2019 Purpose: Research on the physical work environment and employee territorial behavior in the field of organizational behavior is limited. In particular, while the prevalence of territorial behaviors in organizations is not new, little is known about how ...
Monaghan, Natalya +3 more
core +1 more source