Results 201 to 210 of about 811,937 (287)

Alignment of Public Health Agency Demographics With Populations Served. [PDF]

J Public Health Manag Pract
Campbell MD, Pannell GM, McCullough JM.
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Crowdsourcing Cancer Survivors' Perspectives on the Use of Artificial Intelligence and Automation in Financial Hardship Interventions. [PDF]

JCO Oncol Pract
Waters AR, Murray CR, Warner EL, Killela MK, Wheeler SB, Mack JW.   +5 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Access to maternal health services for young women with disabilities in Sub-Saharan Africa: a scoping review protocol. [PDF]

BMJ Open
Pebolo PF, Kimera E, Nkulu Kalengayi FK, Namatovu F.   +3 more
europepmc   +1 more source

Children's services improvement support protocol [PDF]

, 2008

core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

In-situ data of occupant behavior and thermal comfort in 11 offices in a naturally ventilated building during 6 summers. [PDF]

Data Brief
Bal-Fontaine S, Bernaud P, Campagna K, Coulandreau H, Foucquier A, Jay A, Muanda Lutete M.   +6 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Development and pilot of the BC Wildfire Smoke and Extreme Heat Action Plan: empowering patients with climate health readiness. [PDF]

BMJ Open Qual
He R, Shellington E, Barn P, Rideout K, Bueso A, Joshi I, Maddocks S, Camp PG, Crocker M, Coker E, Afshar T, Turvey J, Brigham E.   +12 more
europepmc   +1 more source