Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
How Open Source Software Succeeds? A Review of Research on Success of Open Source Software
Different aspects of Open Source Software (OSS) have been subject of many research in last decades. Among them many researchers have tried to adopt the pervasive literature of information systems success with this special kind of system development and ...
Alireza Amrollahi +2 more
doaj
The Free Software Alternative: Freeware, Open Source Software, and Libraries
: This paper will introduce the reader to the world of freeware and open source software. Following a brief introduction, the author presents an overview of these types of software.
James Edward Corbly
doaj +1 more source
Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez +2 more
wiley +1 more source
Data Mining Techniques for Software Quality Prediction in Open Source Software [PDF]
Software quality monitoring and analysis are among the most productive topics in software engineering research. Their results may be effectively employed by engineers during software development life cycle.
Canaparo Marco, Ronchieri Elisabetta
doaj +1 more source
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Analisa Tingkat Usability Software Open Source ICA-AtoM
Penelitian ini membahas dan mengkaji mengenai seberapa tingkat usability salah satu software bidang arsip digital dengan berbasis opensource yaitu ICA-AtoM. Latar belakang penulisan adalah dengan perkembangan teknologi informasi yang sudah menjadi bagian
Ach. Nizam Rifqi
doaj +1 more source
Free software, Open source software, licenses. A short presentation including a procedure for research software and data dissemination [PDF]
The main goal of this document is to help the research community to understand the basic concepts of software distribution: Free software, Open source software, licenses.
Gomez-Diaz, Teresa, T. Gomez-diaz
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
The usability of open source software: analysis and prospects
Open source communities have successfully developed many pieces of software although most computer users only use proprietary applications. The usability of open source software is often regarded as one reason for this limited distribution. In this paper
Nichols, David M., Twidale, Michael B.
core

