Results 51 to 60 of about 1,342,549 (257)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Patching It Up, Pulling It Forward

Journal of Open Research Software, 2015
An important reason for making any software open source is to encourage code and other community contributions, resulting in more diverse developer communities coalescing around valuable software efforts.
Marlon E. Pierce, Suresh Marru, Chris Mattmann   +2 more
doaj   +1 more source

JOSS: A journal for open source software that is an open source software project

, 2023
A presentation on the Journal of Open Source Software (JOSS) for the IEEE Publication Services and Products Board (PSPB) / Technical Activities Board (TAB) Ad Hoc Committee on Open Peer Review (OPR)
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Sosialisasi Pemanfaatan Software Open Source di SMK Muhammadiyah 1 Surakarta

Warta LPM, 2017
Embrace of open source software (OSS) has not been widespread although users of OSS will gain a lot of benefits and the society and the nation will get many advantages.
Husni Thamrin, Dedi Ary Prasetya, Ady Purna Kurniawan   +2 more
doaj   +1 more source

Software Architecture Degradation in Open Source Software: A Systematic Literature Review

IEEE Access, 2020
Software architecture (SA) has a prominent role in all stages of system development. Given the persistent evolution of software systems over time, SA tends to be eroded or degraded. Such phenomenon is called architectural degradation.
Ahmed Baabad, Hazura Binti Zulzalil, Sa'adah Hassan, Salmi Binti Baharom   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Open source software for libraries and information centers proposed criteria for selecting open source software for managing Arabic libraries

Cybrarians Journal, 2014
The study aimed to identify open source software available for libraries and its various types, especially open source systems for library management, in addition to other software that can be used by specialists in the field of libraries.
Ahmed Khafaga
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Exploiting Open-source Projects to Study Software Design

Informatics in Education, 2007
This article presents an approach to using open-source tools and open-source projects to add realistic and practical examples to a course on software design in a professional master's program of software engineering. Students are encouraged to use object-
Christopher P. FUHRMAN
doaj   +1 more source