Results 71 to 80 of about 1,490,571 (305)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Exploiting Open-source Projects to Study Software Design
Informatics in Education, 2007 This article presents an approach to using open-source tools and open-source projects to add realistic and practical examples to a course on software design in a professional master's program of software engineering. Students are encouraged to use object-
Christopher P. FUHRMAN
doaj +1 more source
Selection and Management of Open Source Software in Libraries
, 2007 Open source software was a revolutionary concept among computer programmers and users. To a certain extent open source solutions could provide an alternative solution to costly commercial software.
Vimal Kumar, V.
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Automating Open Source Software License Information Generation in Software Projects [PDF]
Journal of Systemics, Cybernetics and Informatics, 2018 This publication deals with Open Source Software (OSS) compliance. In a previous publication [1], we presented an organizational-technical concept for ensuring basic OSS compliance. Based on this concept, we now address further aspects that are essential
Sergius Dyck +3 more
doaj
Open Source vs. Proprietary Software: Competition and Compatibility [PDF]
We use a Hotelling linear city model to study competition between open source and proprietary software, where only the producer of the proprietary software aims at maximizing the profit.
Zhaoli Meng
core +2 more sources
Un GIS senza frontiere, Un report della open source free software GIS-GRASS users conference 2002
GEOmedia, 2016 Un GIS senza frontiere, Un report della open source free software GIS-GRASS users conference ...
Marco Ciolli, Paolo Zatelli
doaj +2 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Network Perimeter Defenses Using Open-Source Software
Iraqi Journal of Information & Communication Technology, 2018 network security role grew exponentially in the late several years, especially with the notable amount of attacks that target all types of organizations and services.
Mohammed A. Al-Qassim +1 more
doaj +1 more source