Results 111 to 120 of about 2,750,739 (393)
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher+6 more
wiley +1 more source
Presentation held at Tampere University in the course "Research Ethics" aimed at doctoral students, 8th October 2019. The course examines the responsible conduct of research and the basic questions, rules and principles of research ethics. It highlights recognising and understanding the ethical questions involved at the different phases of the research
openaire +2 more sources
Correspondence: British Thoracic Society guideline on pulmonary rehabilitation in adults: Does objectivity have a sliding scale? [PDF]
This article is made available through the Brunel Open Access Publishing Fund. Copyright © 2014 BMJ Publishing Group Ltd & British Thoracic Society. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non ...
Alison K McConnell+5 more
core +2 more sources
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin+2 more
wiley +1 more source
Sustainability in Publishing: An Open Access Publisher's View
Sustainability is an essential part of the work of publishers. Here, the view of an open access publisher, MDPI, is presented with regards to sustainability within publishing. MDPI’s understanding of sustainability is given and some of the concrete actions it leads to.
openaire +5 more sources
Open access publishing - noble intention, flawed reality.
John Frank, Rosemary Foster, C. Pagliari
semanticscholar +1 more source
Open Access Mandates and the "Fair Dealing" Button [PDF]
We describe the "Fair Dealing Button," a feature designed for authors who have deposited their papers in an Open Access Institutional Repository but have deposited them as "Closed Access" (meaning only the metadata are visible and retrievable, not the full eprint) rather than Open Access.
arxiv
Open, Online and Global: Benefits of BioMedical Journals Going Online and Open [PDF]
The emergence of Internet affords the immense possibility for scientific publications to be indexed, linked, copied, archived, redistributed and searched at ease and at a lower production cost.
Scaria, Dr Vinod
core +1 more source
Open access: brave new world requires bravery [PDF]
The year 2012 heralded significant developments in open access (OA) that impacted the relationships between the major stakeholders in scholarly publishing: researchers, funders, publishers and governments.
Curry, S
core +2 more sources
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source