Results 111 to 120 of about 25,631,015 (286)

Creating open educational resources

open access: yes, 2010
Are you interested in creating your own open educational resources? This unit will help you to write a learning unit and provide you with links to various resources for open-learning materials.
Open University
core  

PDGFRα+/Integrin α2+ Fibroblasts Orchestrate Tumor Budding in Oral Squamous Cell Carcinoma via Mechano‐Metabolic Symbiosis: E‐Cadherin/Integrin α2β1 Adhesion and Mitochondrial Transfer

open access: yesAdvanced Science, EarlyView.
PDGFA/PDGFRα signaling recruits CAFs to OSCC nests, and CAF‐OSCC contact drives tumor budding invasion. Mechanistically, heterotypic adhesion via E‐cadherin/integrin α2β1 activates YAP signaling in OSCC cells, inducing EMT. Concurrently, CAFs transfer mitochondria through TNTs, supplying ATP to fuel invasion.
Yufang Liu   +17 more
wiley   +1 more source

The Dynamic Review Journal: a scholarly archive

open access: yes, 2005
A digital archive, together with its users and its contents, does not exist in isolation - there is a cycle of activity which provides the context for the archive's existence, and which the archive supports through its various roles of information access,
Bailey, Christopher   +6 more
core   +1 more source

The Next Information Revolution - How Open Access will Transform Scholarly Communications [PDF]

open access: yes, 2005
Complaints about spiralling serials costs, lack of service from large commercial publishers, and the inability to meet the information needs of researchers are not new.
David C Prosser, Prosser, David C.
core   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

open access: yesAdvanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun   +15 more
wiley   +1 more source

Cerium Nanoparticle‐Mediated Inhibition of the NSUN2/m5C Axis Suppresses Synovial Aggression in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
A novel epitranscriptomic mechanism in rheumatoid arthritis is uncovered: NSUN2 promotes disease via m5C‐dependent stabilization of ICMT mRNA, fueling the migration and invasion of pathogenic RA FLS. Targeting this axis with engineered nanoparticles (Ce/SAA NPs) effectively inhibits disease progression, presenting a precise therapeutic strategy ...
Ruiru Li   +15 more
wiley   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

open access: yesAdvanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su   +4 more
wiley   +1 more source

Free and open scholarship in the internet age [PDF]

open access: yes, 2010
Describes an action research project on scholarly communication in early stages. Research sites include the Open Access Journal Supports in Canada research team, E-LIS, the Open Archive for Library and Information, Scholarly and Research Communication ...
Morrison, Heather
core   +1 more source

The artistic usage of archives through the Benjaminian lens

open access: yesAcervo, 2019
From Walter Benjamin’s thinking on history, and the usage of archives by artists such as Sara Angelucci, Christian Boltanski, and Angela Grauerholz, we demonstrate that the archive is not a fixed whole, nor an essentially open object but a dynamic ...
Anne Klein, Yvon Lemay
doaj  

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