Results 61 to 70 of about 1,249,788 (300)
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Open Archive Management is the application of open source technologies and archivologic biblioteconomic library information science (LIS) to the organization of files in any size and degree of complexity. It was developed through decades working with the World Wide Web Constortium (W3C) which develops the internet standards and the International ...
openaire +4 more sources
The HD(CP)2 Data Archive for Atmospheric Measurement Data
ISPRS International Journal of Geo-Information, 2016 The archiving of scientific data is a sophisticated mission in nearly all research projects. In this paper, we introduce a new online archive of atmospheric measurement data from the "High definition clouds and precipitation for advancing climate ...
Erasmia Stamnas +3 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
Neuroelectromagnetic Data Archive and Repository: Open-source platform analysis
Aperture NeuroOpen data infrastructures are rapidly reshaping the landscape of neuroscience by enabling greater reproducibility through transparency, reusability, and collaboration, thus providing a foundation for sustainable and scalable scientific progress.
Tracy Brandmeyer +14 more
doaj +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Boom, 2013 The Los Angeles Aqueduct Digital Platform—a joint project of UCLA Library and the Metabolic Studio—is working with other archival repositories to digitize, aggregate, and curate the documentary records of the aqueduct’s construction and history. The new digital platform coincides with the centennial of the aqueduct and makes these vital historical ...
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Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach +23 more
wiley +1 more source
The Sociable Textual Archive: Laying the Groundwork for Linked Bibliographic Entities
KULA, 2019 Much of our scholarly thinking of the ‘social’ in digital editing has been with respect to the human processes of building an archive or an edition. This paper explores the idea of the ‘social’ with respect to the archive’s materials themselves.
Brent Nelson
doaj +1 more source