Results 91 to 100 of about 603,679 (296)
Advanced Science, EarlyView.Our study identifies the HDACs‐STAT3 axis as key regulator for M2 macrophage accumulation in DLBCL. We developed Chid@M2pep‐EVs/TP, a pH‐responsive drug delivery system for M2 macrophage specific chidamide administration. By coupling M2‐targeted chidamide with EVs‐mediated delivery, this system reprograms M2 to M1 via HDAC inhibition and STAT3 ...
Bo Dai +15 more
wiley +1 more source
Archive entrance during open house
, 1995 This negative shows the state archives' entrance during an open house to celebrate the archives' 90th anniversary.
Department of State, Delaware Public Archives
core +1 more source
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
Advanced Science, EarlyView.A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang +19 more
wiley +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
Open Clasp, Open Archive: Intimacy and Distance in an Archival Collaboration
Global Performance Studies, 2021 Chedgzoy K +3 more
openaire +2 more sources
, 2010 Internet for Archives online tutorial has been released as part of the Virtual Training Suite at: http://www.vts.intute.ac.uk/tutorial/archives/ The tutorial, which teaches Internet research skills, has been written by Lisa Jeskins, Promotions and ...
Mimas/Intute +2 more
core
A Tecnologia Open Archives Initiative: Object Reuse and Exchange (OAI-ORE) e suas possibilidades de aplicação em repositórios digitais [PDF]
, 2010 TCC (graduação em Biblioteconomia) - Universidade Federal de Santa Catarina, FlorianópolisEste estudo propõe uma análise da literatura científica a respeito da tecnologia Open Archives Initiative-Object Reuse and Exchange (OAI-ORE), constatando as ...
Souza, Joel de
core
A Perspective on Interactive Theorem Provers in Physics
Advanced Science, EarlyView.Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley +1 more source
The artistic usage of archives through the Benjaminian lens
Acervo, 2019 From Walter Benjamin’s thinking on history, and the usage of archives by artists such as Sara Angelucci, Christian Boltanski, and Angela Grauerholz, we demonstrate that the archive is not a fixed whole, nor an essentially open object but a dynamic ...
Anne Klein, Yvon Lemay
doaj