Results 111 to 120 of about 603,679 (296)

A Microbial Lipid‐ATP Synthase Axis Fuels NK Cell Antitumor Activity

open access: yesAdvanced Science, EarlyView.
This study focuses on the mechanism by which gut microbiota‐derived outer membrane vesicles (OMVs) regulate NK cell antitumor activity. B. intestinalis is identified to decrease extra‐intestinal tumor growth via its OMVs enriched in sphingosine (SP).
Kaiyuan Yu   +16 more
wiley   +1 more source

A user-centred portal for search and retrieval of open-access Italian scholarly literature: the PLEIADI project [PDF]

open access: yes, 2005
The PLEIADI Project (acronym for “Portale per la Letteratura scientifica Elettronica Italiana su Archivi aperti e Depositi Istituzionali”, a portal for Italian scholarly e-literature in open archives and institutional repositories) was born within the ...
Gargiulo, Paola   +3 more
core  

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

open access: yesAdvanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang   +11 more
wiley   +1 more source

Opening Open Jerusalem: OJ International Workshop

open access: yes, 2018
The project’s international workshop, entitled “Opening Open Jerusalem: Tracing Historical Paths through the Jerusalem Archives Digital Platform,” takes place at the Ca’ Foscari University of Venice on 8–9 October 2018.
Open Jerusalem
core  

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

open access: yesAdvanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui   +9 more
wiley   +1 more source

Open Archives initiative: A fast way of integration into global open science

open access: yesChallenges and Issues of Modern Science
Purpose: This article aims to analyze and summarize the practical experience of deploying and integrating platforms for open journals, conferences, and repositories with support for the Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH).
Yurii Tkachov
doaj  

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

open access: yesAdvanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li   +13 more
wiley   +1 more source

Opening* Archaeological Archives

open access: yes, 2018
From the Public Archaeology Twitter Conference.
openaire   +1 more source

Delivery, Management and Access Model for E-prints and Open Access Journals within Further and Higher Education [PDF]

open access: yes, 2005
This study identified three models for open access provision in the UK: (a) the centralised model, where e-prints of articles are first deposited directly into a national archive and then made accessible to users and service providers; (b) the ...
Rowland, Fytton   +15 more
core  

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