Results 31 to 40 of about 603,679 (296)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

E‐prints and the Open Archives Initiative [PDF]

open access: yesLibrary Hi Tech, 2003
The Open Archives Initiative (OAI) was created as a practical way to promote interoperability between e‐print repositories. Although the scope of the OAI has been broadened, e‐print repositories still represent a significant fraction of OAI data providers.
openaire   +2 more sources

Open Access institutional archives: a quantitative study (2006-2010) [PDF]

open access: yes, 2011
Open access publishing is growing in importance, and, in parallel, the role of institutional archives has come to the forefront of discussion within the library community.
Nazim, Mohammad, Mukherjee, Bhaskar
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Building Bridges Across Archives. Open Jerusalem Workshop in Paris

open access: yes, 2017
Building Bridges Across Archives. Designing Open Jerusalem Web Platform The second annual workshop of the ERC project Open Jerusalem will be held at Limonade&Co (Paris) and the French Foreign Office Archives (La Courneuve) on 9-10 May 2017. The workshop
Open Jerusalem
core   +1 more source

Archives as a preponderant factor in an open government ecosystem in today’s Mexico

open access: yesBiblios, 2021
Objective: Evidence of the importance of archives in an open government ecosystem, which supports monitoring citizens’ informational demands. Method: A documentary analysis and an on-site visit were used to determine the state of the art and the current
Zaira Lagunas Ledesma
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Ethical Considerations of Including Gender Information in Open Knowledge Platforms

open access: yesKULA, 2022
In recent years, galleries, libraries, archives, and museums (GLAMs) have sought to leverage open knowledge platforms such as Wikidata to highlight or provide more visibility for traditionally marginalized groups and their work, collections, or ...
Nerissa Lindsey   +2 more
doaj   +1 more source

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