Results 91 to 100 of about 306,323 (300)

Co-curate: Working with Schools and Communities to Add Value to Open Collections

open access: yesJournal of Interactive Media in Education, 2016
Co-Curate North East is a cross-disciplinary initiative involving Newcastle University and partner organisations, working with schools and community groups in the North East of England.
Simon Cotterill   +9 more
doaj   +1 more source

Exploiting open standards in academic web services [PDF]

open access: yes, 2003
In Digital Library-related technologies, there is a whole host of open standards and protocols that are at varying stages of definition or emergence and acceptance or agreement.
Apps, Ann   +2 more
core  

OPTICON: EC Optical Infrared Coordination Network for Astronomy [PDF]

open access: yes, 2001
OPTICON, the ICN Optical Infrared Coordination Network for Astronomy, brings together for the first time the operators of all Europe's medium to large optical-infrared telescopes, the largest corresponding data archives, and several user representatives.
Gilmore, Gerard
core   +2 more sources

CLinNET: An Interpretable and Uncertainty‐Aware Deep Learning Framework for Multi‐Modal Clinical Genomics

open access: yesAdvanced Science, EarlyView.
Identifying disease‐causing genes in neurocognitive disorders remains challenging due to variants of uncertain significance. CLinNET employs dual‐branch neural networks integrating Reactome pathways and Gene Ontology terms to provide pathway‐level interpretability of genomic alterations.
Ivan Bakhshayeshi   +5 more
wiley   +1 more source

A Grape Idea: Competitive Collaboration Is a Win-Win for Regional Archives [PDF]

open access: yes, 2015
In the summer of 2014, Linfield College and Whitman College archivists Rachael Woody and Melissa Salrin teamed up to document the history of the Walla Walla wine industry.
Salrin, Melissa, Woody, Rachael Cristine
core   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

open access: yesAdvanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo   +3 more
wiley   +1 more source

Stress‐Programmed Immune Niches Fuel TNFR2+ Treg Activation and Drive Neoadjuvant Chemotherapy Resistance in Breast Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell sequencing reveals stress‐programmed immune states driving TNFα–TNFR2–mediated Treg activation and therapy resistance in breast cancer, while targeting this axis restores antitumor immunity. ABSTRACT The tumor microenvironment (TME) harbors diverse immune cell states that shape therapeutic outcomes in breast cancer.
Zhibo Shao   +18 more
wiley   +1 more source

Towards Identifying Author Confidence in Biomedical Articles

open access: yesData, 2019
In an era where the volume of medical literature is increasing daily, researchers in the biomedical and clinical areas have joined efforts with language engineers to analyze the large amount of biomedical and molecular biology literature (such as PubMed),
Mihaela Onofrei Plămadă   +2 more
doaj   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

open access: yesAdvanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang   +15 more
wiley   +1 more source

Using OAI-ORE to Transform Digital Repositories into Interoperable Storage and Services Applications

open access: yesCode4Lib Journal, 2009
In the digital age libraries are required to manage large numbers of diverse objects. One advantage of digital objects over fixed physical objects is the flexibility of 'binding' them into publications or other useful aggregated intellectual entities ...
Steve Hitchcock   +5 more
doaj  

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