Results 71 to 80 of about 791,234 (283)

Optimized ANFIS-Genetic Algorithm-Particle Swarm Optimization Model for Estimation of Side Orifices Discharge Coefficient [PDF]

open access: yesNumerical Methods in Civil Engineering, 2018
Generally, side orifices are installed on side walls of the main channels for regulating and controlling water. In this study, a novel hybrid model was developed in order to estimate discharge coefficient of circular and rectangular side orifices.
A. H. Azimi, A. Rajabi, S. Shabanlu
doaj   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

Non-equilibrium stochastic dynamics of open ion channels [PDF]

open access: yes, 2013
We present and discuss a modified version of reaction rate theory (RRT) to describe the passage of a positive ion through a biological ion channel. It takes explicit account of the non-equilibrium nature of the permeation process. Unlike traditional RRT,
Kaufman, Igor   +10 more
core  

Sound radiation in turbulent channel flows [PDF]

open access: yes, 2003
Lighthill’s acoustic analogy is formulated for turbulent channel flow with pressure as the acoustic variable, and integrated over the channel width to produce a two-dimensional inhomogeneous wave equation.
Morfey, Christopher L.   +2 more
core   +1 more source

Coeficiente de rugosidade de Manning para o rio Paracatu Manning roughness coefficient for Paracatu river, Brazil

open access: yesRevista Brasileira de Engenharia Agrícola e Ambiental, 2010
Pela teoria do escoamento em canais abertos, o coeficiente de rugosidade de Manning é um dos principais parâmetros para descrição da vazão sobre uma superfície.
Guilherme B. Lyra   +3 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Channel-facilitated diffusion boosted by particle binding at the channel entrance [PDF]

open access: yes, 2014
We investigate single-file diffusion of Brownian particles in arrays of closely confining microchannels permeated by a variety of attractive optical potentials and connecting two baths with equal particle concentration.
S Pagliara (21860231)   +2 more
core  

Universality of Turbulent Dispersion in a Steady Flow in an Open Channel [PDF]

open access: yes, 2011
We construct a low-dimensional depth-averaged model of turbulent dispersion of tracers in an open channel flow. Two types of the average velocity profile are considered.
Strunin, D. V., D. V. Strunin
core   +1 more source

The uncertainty of the calculative value of the volumetric flow rate in open channel [PDF]

open access: yesArchives of Civil Engineering
The well-known Manning formula is usually used for the calculation of the calculative volumetric flow rate in a river or open canal. The discharge depends on the geometry of the channel, i.e. the water area, the wetted perimeter and the slope, as well as
Leszek Oprychał, Aleksandra Bąk
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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