Results 111 to 120 of about 11,122,566 (354)

Open Data, Grey Data, and Stewardship: Universities at the Privacy Frontier

open access: yes, 2018
As universities recognize the inherent value in the data they collect and hold, they encounter unforeseen challenges in stewarding those data in ways that balance accountability, transparency, and protection of privacy, academic freedom, and intellectual
Borgman, Christine L.
core   +2 more sources

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

Open data, open review and open dialogue in making social sciences plausible [PDF]

open access: yesVuong QH. (2017). Open data, open review and open dialogue in making social sciences plausible. Nature: Scientific Data Updates, 12 December 2017, 2017
Nowadays, protecting trust in social sciences also means engaging in open community dialogue, which helps to safeguard robustness and improve efficiency of research methods. The combination of open data, open review and open dialogue may sound simple but implementation in the real world will not be straightforward.
arxiv  

Chem# - Semantically Enriched Linked Open Chemical Data [PDF]

open access: yes, 2011
The problem: Vast quantities of chemical data (e.g. crystal structures, NMR spectra, experimental reports) are generated every day. The majority of this data is never published, and the data that is published is fragmented,trapped in legacy formats and ...
Adams, Sam   +4 more
core  

The power of microRNA regulation—insights into immunity and metabolism

open access: yesFEBS Letters, EarlyView.
MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto   +2 more
wiley   +1 more source

Cardiovascular disease in a nationwide population of Danish women with polycystic ovary syndrome

open access: yesCardiovascular Diabetology, 2018
Background Polycystic ovary syndrome (PCOS) is associated with obesity and low grade inflammation and the risk for cardiovascular disease (CVD) could be increased in PCOS.
Dorte Glintborg   +4 more
doaj   +1 more source

Identification of novel small molecule inhibitors of ETS transcription factors

open access: yesFEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla   +9 more
wiley   +1 more source

L’universo delle risorse culturali: lampi di genio e azioni concrete. Lightning talks presentati al Convegno AIB CILW 2016

open access: yesAIB Studi, 2017
Sono raccolti sei dei sette lightning talks presentati al Convegno AIB CILW 2016, nell’ambito della sessione aperta al contributo di qualunque studioso delle tematiche proposte nell’incontro.
Gruppo di studio AIB CILW
doaj   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

open access: yesFEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti   +3 more
wiley   +1 more source

Old wine, new bottle? Principi e metodi per una reale innovazione nelle prospettive LIS. Il parere di Marshall Breeding, Mauro Guerrini, David Weinberger, Paul Gabriele Weston, Maja Žumer

open access: yesAIB Studi, 2015
Il saggio è costituito da interviste a Marshall Breeding, Mauro Guerrini, David Weinberger, Paul Gabriele Weston e Maja Žumer, realizzate ponendo tre domande a queste figure riconosciute a livello internazionale. Tramite questo saggio il Gruppo di studio
Gruppo di studio AIB CILW
doaj   +1 more source

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