Results 71 to 80 of about 853,817 (299)

Developing Open RDI and Education in Finnish Universities of Applied Sciences [PDF]

, 2021
Anne Kärki, Seliina Päällysaho, Kaisa Jaalama, Juhani Talvela, Anttoni Lehto, Hannu Hyyppä   +5 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Assessment in Open and Distance Learning System (ODL): A Challenge

Open Praxis, 2013
Assessment is an integral part of the learning process. The traditional practice of assessment has changed to meet the need of the contemporary society.
S. V. S. Chaudhary, Niradhar Dey
doaj   +3 more sources

Open Online Courses in Public Health: experience from Peoples-uni [version 2; referees: 1 approved, 2 approved with reservations]

F1000Research, 2017
Open Online Courses (OOCs) are offered by Peoples-uni at http://ooc.peoples-uni.org to complement the courses run on a separate site for academic credit at http://courses.peoples-uni.org.
Richard F. Heller, Robert Zurynski, Alan Barrett, Omo Oaiya, Rajan Madhok   +4 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Open Online Courses in Public Health: experience from Peoples-uni [version 1; referees: 1 approved, 2 approved with reservations]

F1000Research, 2017
Open Online Courses (OOCs) are offered by Peoples-uni at http://ooc.peoples-uni.org to complement the courses run on a separate site for academic credit at http://courses.peoples-uni.org.
Richard F. Heller, Robert Zurynski, Alan Barrett, Omo Oaiya, Rajan Madhok   +4 more
doaj   +1 more source

The COVID crisis impact on open education in the field of healthcare management. [PDF]

Educ Inf Technol (Dordr), 2023
Bogiatzidis P, Pervou I.
europepmc   +1 more source

Journal of Craniofacial Surgery Open: Welcome to the New Era of Education and Research in the Field of Maxillofacial Surgery

, 2023
Marco Cicciù
openalex   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Encouraging impacts of an Open Education Resource Degree Initiative on college students' progress to degree. [PDF]

High Educ (Dordr), 2022
Griffiths R, Mislevy J, Wang S.
europepmc   +1 more source