Results 121 to 130 of about 815,523 (315)

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Fostering open educational practices [PDF]

open access: yes, 2011
OER are becoming accepted as part of the range of materials that learners and educa- tors can use. However, the methods and practices that enable learners, teachers and institutions to best engage with OER are not yet established and may well be more im- portant in enabling change in education systems than the availability of the resources themselves ...
openaire  

Open education practices in higher education

open access: yes, 2018
Reikšminiai žodžiai: Atvira švietimo praktika; Atviri švietimo ištekliai; Atvirieji švietimo ištekliai; Atvirojo švietimo praktika; Aukštasis mokslas; Kokybinis mokymas; Prieiga prie išteklių, naujovės; Access to resources; Higher education; Innovation; Open Educational Practices; Open Educational Resources; Quality ...
Ehlers, Ulf-Daniel   +3 more
openaire   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

Epilogue: Open Education, social practices, and ecologies of hope

open access: yesALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2016
Steven L. Thorne
doaj   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Commentary: Preparing teachers for open L2TL: Frameworks for critical awareness and transformation

open access: yesALSIC: Apprentissage des Langues et Systèmes d'Information et de Communication, 2016
Jonathon Reinhardt
doaj   +1 more source

Home - About - Disclaimer - Privacy