Results 151 to 160 of about 777,087 (303)

Australian Government public data policy statement [PDF]

open access: yes, 2015
As part of the National Innovation and Science Agenda, the Australian Government has today released its Public Data Policy Statement. This formalises the Government’s commitment to open data and data-driven innovation. Access to and use of the data that
Government of Australia
core  

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Empirical Evaluation of Open Government Data Visualisations [PDF]

open access: yes, 2017
The Open Government Data (OGD) movement has seen governments around the world embrace the concept of opening their data. However, the large amounts of data released have not resulted in wide acceptance of the data by end-users.
Faichney, Jolon   +2 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Western Australian Government open data [PDF]

open access: yes, 2015
The purpose of the Western Australian Whole of Government Open Data Policy is to improve management and use of the public sector\u27s data assets in order to deliver value and benefits for all Western Australians.
Western Australian Land Information Authority
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

TWC data-gov corpus: incrementally generating linked government data from data.gov [PDF]

open access: yes, 2010
The Open Government Directive is making US government data available via websites such as Data.gov for public access. In this paper, we present a Semantic Web based approach that incrementally generates Linked Government Data (LGD) for the US government.
Hendler, James A.   +6 more
core  

Towards a sustainable Open Data ECOsystem : D5.1, Models of allocating roles, tasks and responsibilities in open data ecosystems [PDF]

open access: yes
This Deliverable 5.1 is focussed on the potential impact of different forms of collaborations (including public-private partnerships) to sustainably arrange the distribution of roles, tasks and resources in open data ecosystems.
Chandrasekhar, Ramya   +2 more
core   +1 more source

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